CAS 2471525-44-5

1-Piperazinepentanamide, 4-[4-[[5-chloro-4-[[2-[(methylamino)carbonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

Description:

1-Piperazinepentanamide, 4-[4-[[5-chloro-4-[[2-[(methylamino)carbonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- is a complex organic compound characterized by its multi-functional structure, which includes piperazine and pyrimidine moieties. This compound likely exhibits properties typical of amides, such as moderate solubility in polar solvents and potential for hydrogen bonding due to the presence of amine and carbonyl groups. The presence of chlorine and methoxy groups may influence its reactivity and biological activity, potentially enhancing its pharmacological profile. Given its intricate structure, it may interact with various biological targets, making it of interest in medicinal chemistry. The compound's molecular weight, stability, and specific reactivity would depend on its precise arrangement of functional groups, which can affect its behavior in chemical reactions and biological systems. Overall, this compound represents a class of molecules that may have applications in drug development or as research tools in biochemistry.

Formula: C₄₁H₄₃ClN₁₀O₇

Synonyms:

• FAK PROTAC B5
• 1-Piperazinepentanamide, 4-[4-[[5-chloro-4-[[2-[(methylamino)carbonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
• 2-{[5-chloro-2-({4-[4-(4-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]carbamoyl}butyl)piperazin-1-yl]-2-methoxyphenyl}amino)pyrimidin-4-yl]amino}-N-methylbenzamide

FAK PROTAC B5

CAS: 2471525-44-5

FAK PROTAC B5: a degrader with 14.9 nM IC50, strong degradation, anti-growth, good plasma stability, and fair permeability.

Formula: C₄₁H₄₃ClN₁₀O₇

Color and Shape: Solid

Molecular weight: 823.3

Ref: TM-T74281