CAS 24719-82-2

N6-Threonylcarbamoyladenosine

Description:

N6-Threonylcarbamoyladenosine is a modified nucleoside that features a threonyl carbamoyl group attached to the nitrogen at the 6-position of the adenine base. This compound is part of a broader class of nucleosides that play significant roles in various biological processes, including cellular signaling and metabolism. Its structure includes a ribose sugar moiety, which is characteristic of nucleosides, and the presence of the threonyl carbamoyl group can influence its biochemical properties, such as solubility and interaction with enzymes or receptors. N6-Threonylcarbamoyladenosine may exhibit unique pharmacological activities, making it of interest in biochemical research and potential therapeutic applications. The compound's CAS number, 24719-82-2, serves as a unique identifier for regulatory and research purposes. Overall, the study of such modified nucleosides contributes to our understanding of nucleic acid chemistry and the development of novel biomolecules for therapeutic use.

Formula: C₁₅H₂₀N₆O₈

InChI: InChI=1S/C15H20N6O8/c1-5(23)7(14(26)27)19-15(28)20-11-8-12(17-3-16-11)21(4-18-8)13-10(25)9(24)6(2-22)29-13/h3-7,9-10,13,22-25H,2H2,1H3,(H,26,27)(H2,16,17,19,20,28)/t5-,6-,7+,9-,10-,13-/m1/s1

InChI key: InChIKey=UNUYMBPXEFMLNW-DWVDDHQFSA-N

SMILES: N(C(N[C@@H]([C@@H](C)O)C(O)=O)=O)C1=C2C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)=NC=N1

Synonyms:

• N-[(9-β-D-Ribofuranosylpurin-6-yl)carbamoyl]threonine
• L-Threonine, N-[[(9-β-D-ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-
• N-(6-Nebularinylcarbamoyl)threonine
• Threonine, N-[(9-β-D-ribofuranosyl-9H-purin-6-yl)carbamoyl]-, L-
• N-[[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-L-threonine

N6-[((1S,2R)-1-Carboxy-2-hydroxybutylamino)carbonyl]adenosine sodium salt

CAS: 24719-82-2

Formula: C₁₅H₂₀N₆O₈

Purity: 98%

Color and Shape: Liquid

Molecular weight: 412.3547

Ref: IN-DA00BC6B

T6A

CAS: 24719-82-2

T6A

Purity: ≥98%

Molecular weight: 412.35g/mol

Ref: 54-BUP17893

N6-Threonylcarbamoyl Adenosine

CAS: 24719-82-2

Formula: C₁₅H₂₀N₆O₈

Molecular weight: 412.36

Ref: 4Z-A-267053

N6-(N-Threonylcarbonyl)adenosine

Controlled Product

CAS: 24719-82-2

Applications N6-(N-Threonylcarbonyl)adenosine is an essential modified nucleoside found in tRNA responsible for ANN codons in all three domains of life. It is also a biological marker in neoplastic diseases.
References Miyauchi, K., et al.: Nat. Chem. Biol., 9, 105 (2013); Deutsch, C., et al.: J. Biol. Chem., 287, 13666 (2012)

Formula: C₁₅H₂₀N₆O₈

Color and Shape: Neat

Molecular weight: 412.35

Ref: TR-T405560

N6-Carbamoylthreonyladenosine sodium salt

CAS: 24719-82-2

N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.

Formula: C₁₅H₁₉N₆O₈·Na

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 434.34 g/mol

Ref: 3D-NC06332

T6A

CAS: 24719-82-2

T6A (N6-Threonylcarbamoyladenosine) is a ubiquitously conserved nucleoside, which is essential for modification.

Formula: C₁₅H₂₀N₆O₈

Purity: 98.95%

Color and Shape: Solid

Molecular weight: 412.35

Ref: TM-T34765