CAS 2472802-77-8

2-Pyrazinecarboxamide, N-[4-[4-amino-6-ethynyl-5-(3-quinolinyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]bicyclo[2.2.1]hept-1-yl]-5-methyl-

Description:

2-Pyrazinecarboxamide, N-[4-[4-amino-6-ethynyl-5-(3-quinolinyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]bicyclo[2.2.1]hept-1-yl]-5-methyl- is a complex organic compound characterized by its unique structural features, including a pyrazinecarboxamide moiety and a bicyclic structure. This compound exhibits potential biological activity, often investigated for its role in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. The presence of functional groups such as amines and ethynyl groups suggests reactivity that may be exploited in further chemical modifications or in the synthesis of derivatives. Its molecular structure indicates potential interactions with biological targets, making it a candidate for research in areas such as cancer therapy or other therapeutic applications. The compound's solubility, stability, and bioavailability would be critical factors in its practical use, and these properties would typically be assessed through various analytical techniques. Overall, this compound represents a significant interest in the field of drug discovery and development.

Formula: C₃₀H₂₆N₈O

Synonyms:

• 2-Pyrazinecarboxamide, N-[4-[4-amino-6-ethynyl-5-(3-quinolinyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]bicyclo[2.2.1]hept-1-yl]-5-methyl-

EGFR-IN-125

CAS: 2472802-77-8

EGFR-IN-125 (example 37) is a potent EGFR inhibitor with IC50 values of <0.3 nM for EGFR(d746-750/T790M/C797S), 0.52 nM for EGFR(L858R/T790M/C797S), 0.5 nM for EGFR(d746-750/C797S), 0.69 nM for EGFR(L858R/C797S), and 0.92 nM for EGFR (wild type).

Formula: C₃₀H₂₆N₈O

Color and Shape: Solid

Molecular weight: 514.58

Ref: TM-T204450