CAS 24751-67-5

5-(Azidomethyl)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 24751-67-5

5-(Azidomethyl)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Purity: 98%

Molecular weight: 299.24g/mol

Ref: 54-OR1067184

5-(Azidomethyl)uridine

CAS: 24751-67-5

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Azido-nucleosides

Formula: C₁₀H₁₃N₅O₆

Color and Shape: Solid

Molecular weight: 299.24

Ref: TM-TNU0333

5-(Azidomethyl)uridine

CAS: 24751-67-5

5-(Azidomethyl)uridine (5-AZA-U) is a cytosolic nucleoside analog that inhibits the replication of herpes simplex virus type 1 (HSV-1). It is resistant to degradation by cellular nucleases and is fluorescent, making it a clickable substrate for microscopy. 5-AZA-U has been shown to inhibit the transcription of viral DNA and the synthesis of viral proteins in mammalian cells. This drug has also been shown to be effective against cancer and hepatitis B virus (HBV). 5-AZA-U can be used as an antiviral agent because of its ability to inhibit the posttranscriptional gene expression of HSV-1. 5-(Azidomethyl)uridine is also an analog of uridine, which can be used to study intracellular signaling pathways that regulate proliferation, differentiation, or apoptosis in mammalian cells.

Formula: C₁₀H₁₃N₅O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 299.24 g/mol

Ref: 3D-NA162992