CymitQuimica logo

CAS 247564-71-2

:

2,3,6-Trifluorophenylboronic acid

Description:
2,3,6-Trifluorophenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that is substituted with three fluorine atoms at the 2, 3, and 6 positions. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the boronic acid group, which can engage in hydrogen bonding. The trifluoromethyl substitutions enhance its reactivity and influence its electronic properties, making it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of fluorine atoms can also impart unique characteristics, such as increased lipophilicity and altered metabolic stability. Additionally, 2,3,6-trifluorophenylboronic acid can participate in various coupling reactions, including Suzuki-Miyaura cross-coupling, which is widely used in the formation of carbon-carbon bonds. Its chemical stability and reactivity make it a useful reagent in synthetic organic chemistry.
Formula:C6H4BF3O2
InChI:InChI=1/C6H4BF3O2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2,11-12H
SMILES:c1c(cc(c(c1B(O)O)F)F)F
Synonyms:
  • 2,3,6-Trifluorobenzeneboronic acid
  • Dimethyl(2-Oxo-2-Phenylethyl)Sulfonium Tetrafluoroborate
  • (2,3,5-Trifluorophenyl)Boronic Acid
  • 2,3,5-TRIFLUOROPHENYLBORONIC ACID
  • RARECHEM AH PB 0123
  • 2,3,5-TRIFLUOROBENZENEBORONIC ACID
  • 2,4,5-TRIFLUOROPHENYLBORONIC ACID
  • 2,4,5-TRIFLUOROBENZENEBORONIC ACID
  • RARECHEM AH PB 0119
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.