CAS 24769-58-2

Acid-TRH

Description:

Acid-TRH, with the CAS number 24769-58-2, is a synthetic compound that is primarily recognized for its role as a biochemical agent. It is often associated with its function as a peptide or a derivative of a peptide, which may influence various physiological processes. The substance is characterized by its ability to interact with specific receptors in biological systems, potentially affecting hormonal regulation and neurotransmission. Acid-TRH is typically soluble in water and exhibits stability under standard laboratory conditions, although its reactivity may vary depending on the presence of other chemical species. Its applications can span across research in neurobiology and endocrinology, where it may be used to study the mechanisms of action of related hormones or to explore therapeutic avenues for conditions influenced by these pathways. As with many chemical substances, proper handling and safety protocols should be observed to mitigate any potential hazards associated with its use.

Formula: C₁₆H₂₁N₅O₅

InChI: InChI=1S/C16H21N5O5/c22-13-4-3-10(19-13)14(23)20-11(6-9-7-17-8-18-9)15(24)21-5-1-2-12(21)16(25)26/h7-8,10-12H,1-6H2,(H,17,18)(H,19,22)(H,20,23)(H,25,26)/t10-,11-,12-/m0/s1

InChI key: InChIKey=ITYONPBTNRIEBA-SRVKXCTJSA-N

SMILES: C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCC(=O)N2)(=O)N3[C@H](C(O)=O)CCC3

Synonyms:

• 5-Oxo-<span class="text-smallcaps">L</smallcap>-prolyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline
• 5-Oxo-Pro-His-Pro
• 5-oxo-L-prolyl-3-(4H-imidazol-4-yl)-L-alanyl-L-proline
• <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-(5-oxo-<smallcap>L</smallcap>-prolyl)-<smallcap>L</span>-histidyl]-
• <span class="text-smallcaps">L</smallcap>-Proline, 5-oxo-<smallcap>L</smallcap>-prolyl-<smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Pyroglutamyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-proline
• Acid thyroliberin
• Acid-TRH
• Deamidated TRH
• Deamido-TRH
• Deamido-thyrotropin-releasing factor
• Deamino-thyrotropin releasing hormone
• Proline, 1-[N-(5-oxo-<span class="text-smallcaps">L</smallcap>-prolyl)-<smallcap>L</smallcap>-histidyl]-, <smallcap>L</span>-
• Pyr-His-Pro-OH
• TRH (free acid)
• TRH acid
• Thyrotropin-releasing hormone free acid
• Trh-Oh
• L-Proline, 5-oxo-L-prolyl-L-histidyl-
• L-Proline, 1-[N-(5-oxo-L-prolyl)-L-histidyl]-
• Proline, 1-[N-(5-oxo-L-prolyl)-L-histidyl]-, L-
• 5-Oxo-L-prolyl-L-histidyl-L-proline

TRH (free acid)

CAS: 24769-58-2

Bachem ID: 4002023.

Formula: C₁₆H₂₁N₅O₅

Purity: > 98%

Color and Shape: Whitish Powder

Molecular weight: 363.37

Ref: 01-4002023

L-Proline, 5-oxo-L-prolyl-L-histidyl-

CAS: 24769-58-2

Formula: C₁₆H₂₁N₅O₅

Purity: 95%

Molecular weight: 363.3684

Ref: IN-DA002PE3

Thyrotropin-Releasing Hormone (TRH), Free Acid

CAS: 24769-58-2

Thyrotropin-Releasing Hormone (TRH), Free Acid

Purity: ≥95%

Molecular weight: 363.37g/mol

Ref: 54-BUP06522

Protirelin EP Impurity D

CAS: 24769-58-2

Formula: C₁₆H₂₁N₅O₅

Color and Shape: White To Off-White Solid

Molecular weight: 363.37

Ref: 4Z-PP-357005

Thyrotropin-Releasing Hormone (TRH), Free Acid

CAS: 24769-58-2

TRH, a free acid, regulates thyroid hormone levels and has other thyroid/non-thyroid effects.

Formula: C₁₆H₂₁N₅O₅

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 363.37

Ref: TM-T7407

Deamido-TRH

Controlled Product

CAS: 24769-58-2

Formula: C₁₆H₂₁N₅O₅

Color and Shape: Neat

Molecular weight: 363.368

Ref: TR-D820640

Protirelin EP Impurity D

CAS: 24769-58-2

Formula: C₁₆H₂₁N₅O₅

Molecular weight: 363.37

Ref: ST-EA-CP-P233002

TRH (free acid) Pyr-His-Pro-OH

CAS: 24769-58-2

TRH is a hormone that regulates the metabolic rate and stimulates the pancreas to release insulin. It also has been shown to be involved in regulating locomotor activity and is used in clinical trials for its potential therapeutic effects on Alzheimer’s disease. TRH binds to receptors on gland cells where it activates adenylate cyclase and increases intracellular levels of cAMP, which leads to an increase in cytosolic calcium concentration. TRH also binds to receptors on nerve cells and causes these cells to release neurotransmitters such as dopamine and serotonin. TRH is synthesized by the thyroid gland, pituitary gland, hypothalamus, or other tissues in response to stress or illness. TRH can be administered orally or injected intravenously; it is not active when taken orally because it is broken down by digestive enzymes before reaching the systemic circulation.

Formula: C₁₆H₂₁N₅O₅

Purity: Min. 95%

Molecular weight: 363.37 g/mol

Ref: 3D-FT109399