CAS 2480226-06-8

Simufilam dihydrochloride

Description:

Simufilam dihydrochloride, identified by its CAS number 2480226-06-8, is a small molecule compound that has garnered attention in the field of neurodegenerative disease research, particularly Alzheimer's disease. It functions as a modulator of the sigma-1 receptor, which plays a crucial role in cellular signaling and neuroprotection. The compound is characterized by its ability to stabilize the structure of the tau protein, potentially preventing the formation of neurofibrillary tangles associated with Alzheimer's pathology. Simufilam is typically administered in its dihydrochloride salt form to enhance solubility and bioavailability. Its pharmacological profile suggests a favorable safety and tolerability profile in clinical studies, making it a candidate for further investigation in therapeutic applications. As research continues, the precise mechanisms of action and long-term effects of Simufilam dihydrochloride are being explored to better understand its potential benefits in treating cognitive decline and related disorders.

Formula: C₁₅H₂₂ClN₃O

Synonyms:

• Inhibitor,PTI-125,Simufilam,inhibit,PTI 125,PTI125,Simufilam dihydrochloride
• PTI-125 dihydrochloride
• Simufilam dihydrochloride
• Simufilam 2hcl
• PTI-125 HCl
• 1-Benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-2-one dihydrochloride
• Simufilam HCl
• PTI-125 HCl(1224591-33-6 free base)
• Simufilamum HCl

Simufilam dihydrochloride

CAS: 2480226-06-8

Formula: C₁₅H₂₃Cl₂N₃O

Purity: 95%

Color and Shape: Solid

Molecular weight: 332.2686

Ref: IN-DA01X5O9

Simufilam dihydrochloride

CAS: 2480226-06-8

Simufilam dihydrochloride

Purity: ≥98%

Molecular weight: 332.3g/mol

Ref: 54-BUP12235

Simufilam dihydrochloride

CAS: 2480226-06-8

Simufilam dihydrochloride is an oral, low-toxic FLNA activator for Alzheimer's research, restoring FLNA structure and function.

Formula: C₁₅H₂₃Cl₂N₃O

Purity: 98.83%

Color and Shape: Solid

Molecular weight: 332.3

Ref: TM-T9172