CAS 2480283-75-6

1,3,4-Thiadiazole-2-carboxylic acid, 5-[[4-(aminosulfonyl)benzoyl]amino]-, ethyl ester

Description:

1,3,4-Thiadiazole-2-carboxylic acid, 5-[[4-(aminosulfonyl)benzoyl]amino]-, ethyl ester is a chemical compound characterized by its unique structure, which includes a thiadiazole ring, a carboxylic acid functional group, and an ethyl ester moiety. The presence of the sulfonamide group, derived from 4-aminobenzenesulfonic acid, suggests potential biological activity, particularly in medicinal chemistry. This compound may exhibit properties such as antimicrobial or anti-inflammatory effects, making it of interest in pharmaceutical research. Its molecular structure allows for various interactions, including hydrogen bonding and π-π stacking, which can influence its solubility and reactivity. The ethyl ester group enhances lipophilicity, potentially improving the compound's bioavailability. Additionally, the thiadiazole ring is known for its role in various biological activities, including as a scaffold for drug development. Overall, this compound represents a complex structure with potential applications in drug discovery and development, warranting further investigation into its pharmacological properties and mechanisms of action.

Formula: C₁₂H₁₂N₄O₅S₂

Synonyms:

• hCAI/II-IN-2
• 1,3,4-Thiadiazole-2-carboxylic acid, 5-[[4-(aminosulfonyl)benzoyl]amino]-, ethyl ester

hCAI/II-IN-2

CAS: 2480283-75-6

hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.

Formula: C₁₂H₁₂N₄O₅S₂

Color and Shape: Solid

Molecular weight: 356.38

Ref: TM-T61282