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CAS 248282-07-7

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Laquinimod sodium

Description:
Laquinimod sodium is a synthetic compound primarily investigated for its potential therapeutic applications in treating autoimmune diseases, particularly multiple sclerosis. It functions as an immunomodulator, influencing the immune response without directly suppressing it. The substance is characterized by its ability to cross the blood-brain barrier, which is crucial for its efficacy in neurological conditions. Laquinimod sodium exhibits anti-inflammatory properties and has been shown to reduce the frequency of relapses in multiple sclerosis patients in clinical trials. Its mechanism of action involves modulation of cytokine production and enhancement of neuroprotective factors. The compound is typically administered orally and is well-tolerated, with a safety profile that has been evaluated in various studies. However, like all medications, it may have side effects, which can vary among individuals. Ongoing research continues to explore its full potential and applications in other inflammatory and neurodegenerative disorders.
Formula:C19H17ClN2O3·Na
InChI:InChI=1S/C19H17ClN2O3.Na/c1-3-22(12-8-5-4-6-9-12)19(25)16-17(23)15-13(20)10-7-11-14(15)21(2)18(16)24;/h4-11,23H,3H2,1-2H3;
InChI key:InChIKey=AHIFNCNCUYJCOR-UHFFFAOYSA-N
SMILES:OC=1C=2C(N(C)C(=O)C1C(N(CC)C3=CC=CC=C3)=O)=CC=CC2Cl.[Na]
Synonyms:
  • N-Ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide sodium salt
  • 3-Quinolinecarboxamide, 5-chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-, sodium salt (1:1)
  • 3-Quinolinecarboxamide, 5-chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-, sodium salt
  • Laquinimod sodium
  • ABR 215062 sodium
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