CAS 2484719-16-4

3-Deoxy-3S-chloroabiraterone

Controlled Product

CAS: 2484719-16-4

Formula: C₂₄H₃₀ClN

Color and Shape: Neat

Molecular weight: 367.95

Ref: TR-D232532

3-Deoxy-3-chloroabiraterone (Mixture of Diastereomers)

Controlled Product

CAS: 2484719-16-4

Applications 3-Deoxy-3-chloroabiraterone is an impurtiy of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

Formula: C₂₄H₃₀ClN

Color and Shape: Neat

Molecular weight: 367.955

Ref: TR-D232530

3-Deoxy-3S-Chloroabiraterone

CAS: 2484719-16-4

Formula: C₂₄H₃₀ClN

Molecular weight: 367.96

Ref: ST-EA-CP-A67095