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CAS 2488-18-8

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Boc-Met-Onp

Description:
Boc-Met-Onp, also known as N-Boc-L-methionine p-nitrophenyl ester, is a chemical compound commonly used in peptide synthesis and biochemistry. It features a tert-butyloxycarbonyl (Boc) protecting group on the amino group of methionine, which facilitates the selective reaction of the carboxylic acid during peptide formation. The p-nitrophenyl ester moiety serves as a good leaving group, making it useful for coupling reactions. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its stability under standard laboratory conditions allows for ease of handling, although it should be stored in a cool, dry place away from light to prevent degradation. Boc-Met-Onp is often utilized in the synthesis of peptides where the methionine residue is required, and its reactivity can be exploited in various chemical transformations, making it a valuable tool in organic and medicinal chemistry.
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