CAS 2490-91-7

3-deoxy-D-glucose

Description:

3-Deoxy-D-glucose, with the CAS number 2490-91-7, is a monosaccharide and an analog of glucose. It is characterized by the absence of an oxygen atom at the third carbon position, which distinguishes it from glucose. This modification affects its biochemical properties and metabolic pathways. 3-Deoxy-D-glucose is a white crystalline solid that is soluble in water, making it suitable for various biochemical applications. It is often used in research to study glucose metabolism and transport, as it can inhibit glycolysis and serve as a competitive inhibitor of glucose uptake in cells. Additionally, it has potential applications in cancer research due to its ability to interfere with the energy metabolism of rapidly dividing cells. The compound is typically stable under standard laboratory conditions but should be handled with care, as with all chemical substances. Its structural formula and properties make it a valuable tool in both biochemical research and potential therapeutic applications.

Formula: C₆H₁₂O₅

InChI: InChI=1/C6H12O5/c7-2-5-3(8)1-4(9)6(10)11-5/h3-10H,1-2H2/t3-,4-,5?,6?/m0/s1

SMILES: C1[C@@H](C(CO)OC([C@H]1O)O)O

Synonyms:

• 3-Deoxyglucose
• D-ribo-Hexose, 3-deoxy-
• 3-deoxy-D-ribo-hexose

(2R,4S,5R)-2,4,5,6-Tetrahydroxyhexanal

CAS: 2490-91-7

Formula: C₆H₁₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 164.1565

Ref: IN-DA002PSW

3-Deoxy-D-glucose

CAS: 2490-91-7

3-Deoxy-D-glucose

Molecular weight: 164.16g/mol

Ref: 54-BISY005

3-Deoxy-D-glucose

CAS: 2490-91-7

Formula: C₆H₁₂O₅S

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 164.16

Ref: 7W-GC4203

3-Deoxy-D-glucose

CAS: 2490-91-7

3-Deoxy-D-glucose (3DG) is a molecule that belongs to the class of carbohydrates. It is an analog of D-glucose, which is the key substrate for the production of energy in mammalian cells. 3DG has been shown to inhibit the uptake of glucose by trypanosomes and also inhibits glycolysis in mammalian cells. The inhibition of glycolysis may be due to its ability to prevent the phosphorylation of glucose by hexokinase, thus blocking the conversion of glucose into glucose 6-phosphate. 3DG is biosynthesized from d-xylose, which is a five carbon sugar that can be oxidized to form CO2 and H2O.

Formula: C₆H₁₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 164.16 g/mol

Ref: 3D-MD03580

3-Deoxy-D-glucose

Controlled Product

CAS: 2490-91-7

Applications Used for treating seizure and paroxysmal disorders.
References Tetaud, E., et al.: Biochem. J., 317, 353 (1996), Manning, S., et al.: J. Biol. Chem., 277, 30942 (2002), Peier, A., et al.: Science, 296, 2046 (2002),

Formula: C₆H₁₂O₅

Color and Shape: Neat

Molecular weight: 164.16

Ref: TR-D239040