CAS 24916-50-5

Spiramycin I

Description:

Spiramycin I is a macrolide antibiotic that is primarily derived from the bacterium Streptomyces ambofaciens. It is known for its effectiveness against a variety of Gram-positive bacteria and some Gram-negative organisms, making it useful in treating infections, particularly in respiratory and soft tissue infections. The chemical structure of Spiramycin I features a large lactone ring, which is characteristic of macrolides, and it contains multiple sugar moieties that contribute to its biological activity. Spiramycin I exhibits a mechanism of action that involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. It is often administered orally and is well-absorbed in the gastrointestinal tract. Additionally, Spiramycin I has been noted for its relatively low toxicity profile, making it a preferred choice in certain clinical scenarios, including use during pregnancy. However, as with all antibiotics, it is essential to use Spiramycin I judiciously to prevent the development of antibiotic resistance.

Formula: C₄₃H₇₄N₂O₁₄

InChI: InChI=1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26-,27-,28+,29+,30+,31-,32+,34+,35+,36-,37-,38-,39+,40+,41+,42+,43-/m1/s1

InChI key: InChIKey=ACTOXUHEUCPTEW-CEUOBAOPSA-N

SMILES: O([C@H]1[C@@H](CC=O)C[C@@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](N(C)C)CC2)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]1OC)[C@H]3[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]4C[C@@](C)(O)[C@@H](O)[C@H](C)O4)[C@@H](C)O3

Synonyms:

• Oxacyclohexadecane, leucomycin V deriv.
• Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-
• Spiramycin A
• Foromacidin A
• Leucomycin V, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, [9(2R,5S,6R)]-

Spiramycin

CAS: 24916-50-5

Formula: C₄₃H₇₄N₂O₁₄

Purity: 90%

Color and Shape: Solid

Molecular weight: 843.0527

Ref: IN-DA002PUV

2-((4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-Dihydroxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-10-

CAS: 24916-50-5

2-((4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-(((2S,3R,4R,5S,6R)-5-(((2S,4R,5S,6S)-4,5-Dihydroxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-10-

Molecular weight: 843.05g/mol

Ref: 54-OR1024586

Spiramycin I

CAS: 24916-50-5

Formula: C₄₃H₇₄N₂O₁₄

Color and Shape: White To Off-White Solid

Molecular weight: 843.07

Ref: 4Z-S-4312

Spiramycin I

Controlled Product

CAS: 24916-50-5

Formula: C₄₃H₇₄N₂O₁₄

Color and Shape: Neat

Molecular weight: 843.05

Ref: 04-CA16972910

Spiramycin I (>90%)

CAS: 24916-50-5

Applications Antibiotic substance classified in the erythromycin-carbomycin group.
References Sous, H., et al.: Arzneim.-Forsch., 8, 386 (1958), Mitscher, et al.: J. Antibiot., 26, 55 (1973)

Formula: C₄₃H₇₄N₂O₁₄

Color and Shape: White To Off-White

Molecular weight: 843.05

Ref: TR-S682300

Spiramycin I

CAS: 24916-50-5

Formula: C₄₃H₇₄N₂O₁₄

Molecular weight: 843.07

Ref: ST-EA-CP-S21009

Spiramycin I

CAS: 24916-50-5

Spiramycin I is a macrolide antibiotic with action on bacterial protein synthesis inhibition and is used for treating toxoplasmosis and bacterial infections.

Formula: C₄₃H₇₄N₂O₁₄

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 843.05 g/mol

Ref: 3D-AS16859