CAS 24916-51-6: Acetylspiramycin

Description: Acetylspiramycin is a macrolide antibiotic derived from the fermentation of the bacterium *Streptomyces ambofaciens*. It is primarily used in veterinary medicine for the treatment of various bacterial infections in animals, particularly in livestock and poultry. The compound exhibits antibacterial activity against a range of Gram-positive bacteria and some Gram-negative bacteria, making it effective in treating respiratory and gastrointestinal infections. Acetylspiramycin works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. It is characterized by its relatively low toxicity and good safety profile in animals when used as directed. The substance is typically administered orally or via injection, depending on the specific formulation and intended use. Its chemical structure includes a large lactone ring, which is a hallmark of macrolide antibiotics, contributing to its mechanism of action and pharmacological properties. As with all antibiotics, careful consideration of dosage and potential resistance development is essential in its application.

Formula: C₄₅H₇₆N₂O₁₅

InChI: InChI=1S/C45H76N2O15/c1-25-22-31(20-21-48)41(62-44-39(51)38(47(10)11)40(28(4)58-44)61-37-24-45(7,53)43(52)29(5)57-37)42(54-12)34(59-30(6)49)23-35(50)55-26(2)16-14-13-15-17-33(25)60-36-19-18-32(46(8)9)27(3)56-36/h13-15,17,21,25-29,31-34,36-44,51-53H,16,18-20,22-24H2,1-12H3/b14-13+,17-15+/t25-,26-,27-,28-,29+,31+,32+,33+,34-,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1

InChI key: InChIKey=ZPCCSZFPOXBNDL-ZSTSFXQOSA-N

SMILES: O=CCC1CC(C)C(OC2OC(C)C(N(C)C)CC2)C=CC=CCC(OC(=O)CC(OC(=O)C)C(OC)C1OC3OC(C)C(OC4OC(C)C(O)C(O)(C)C4)C(N(C)C)C3O)C

Synonyms:

• (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate (non-preferred name)
• (4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2S,5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate (non-preferred name)
• Acetyl Spiramycin
• Foromacidin B
• Foromacidine B
• Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate
• Leucomycin V, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate, [9(2R,5S,6R)]-
• Oxacyclohexadecane, leucomycin V deriv.
• Spiramycin 2
• Spiramycin B
• Spiramycin II

Acetylspiramycin

CAS: 24916-51-6

Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.

• Formula: C₄₅H₇₆N₂O₁₅
• Purity: ≥98%
• Color and Shape: White Powder
• Molecular weight: 885.09

Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-acetate

CAS: 24916-51-6

• Formula: C₄₅H₇₆N₂O₁₅
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 885.0893

Acetylspiramycin

CAS: 24916-51-6

• Purity: ≥98%
• Molecular weight: 885.09g/mol

Spiramycin II (Acetylspiramycin)

CAS: 24916-51-6

• Formula: C₄₅H₇₆N₂O₁₅
• Molecular weight: 885.10

Acetylspiramycin - Mixture of components

CAS: 24916-51-6

Please enquire for more information about Acetylspiramycin - Mixture of components including the price, delivery …

• Formula: C₄₅H₇₆N₂O₁₅
• Color and Shape: Powder
• Molecular weight: 885.09 g/mol

Acetylspiramycin (Contains Monoacetyl, Diacetyl and Triacetyl)

CAS: 24916-51-6

Applications Antibiotic substance classified in the erythromycin-carbomycin group.A representative consisted of 3% mono, 49% diacetyl …

• Formula: C₄₇H₇₈N₂O₁₆(diacetyl)
• Color and Shape: Neat
• Molecular weight: 927.14