CAS 24916-52-7

Spiramycin III

Description:

Spiramycin III is a macrolide antibiotic that is derived from the bacterium Streptomyces ambofaciens. It is part of a larger group of spiramycin compounds, which are known for their antibacterial properties, particularly against Gram-positive bacteria and some Gram-negative organisms. The chemical structure of Spiramycin III features a large lactone ring, which is characteristic of macrolides, and it contains multiple sugar moieties that contribute to its biological activity. This compound is often used in veterinary medicine and has applications in treating infections in livestock. Spiramycin III exhibits a mechanism of action that involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. It is generally well-tolerated, but like other antibiotics, it may cause side effects and should be used judiciously to avoid the development of antibiotic resistance. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, can vary based on the route of administration and the specific formulation used.

Formula: C₄₆H₇₈N₂O₁₅

InChI: InChI=1S/C46H78N2O15/c1-13-35(50)60-34-24-36(51)56-27(3)17-15-14-16-18-33(61-37-20-19-32(47(8)9)28(4)57-37)26(2)23-31(21-22-49)42(43(34)55-12)63-45-40(52)39(48(10)11)41(29(5)59-45)62-38-25-46(7,54)44(53)30(6)58-38/h14-16,18,22,26-34,37-45,52-54H,13,17,19-21,23-25H2,1-12H3/b15-14+,18-16+/t26-,27-,28-,29-,30+,31+,32+,33+,34-,37+,38+,39-,40-,41-,42+,43+,44+,45+,46-/m1/s1

InChI key: InChIKey=HSZLKTCKAYXVBX-LYIMTGTFSA-N

SMILES: O([C@@H]1[C@@H](OC)[C@H](OC(CC)=O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](O[C@@H]2O[C@H](C)[C@@H](N(C)C)CC2)[C@H](C)C[C@@H]1CC=O)[C@H]3[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]4C[C@@](C)(O)[C@@H](O)[C@H](C)O4)[C@@H](C)O3

Synonyms:

• Foromacidin C
• Foromacidine C
• Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-propanoate
• Leucomycin V, 9-O-[5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-, 3-propanoate, [9(2R,5S,6R)]-
• Oxacyclohexadecane, leucomycin V deriv.
• Spiramycin 3
• Spiramycin C
• Spiramycin III

Spiramycin III

CAS: 24916-52-7

Spiramycin III is an antibiotic within the erythromycin/carbomycin group of compounds.

Formula: C₄₆H₇₈N₂O₁₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 899.129

Ref: TM-T26206

Spiramycin III

CAS: 24916-52-7

Formula: C₄₆H₇₈N₂O₁₅

Molecular weight: 899.13

Ref: 4Z-S-4317

Spiramycin - mixture of spiramycins

CAS: 24916-52-7

Spiramycin III is an antibiotic that inhibits bacterial protein synthesis. It binds to the 16S ribosomal RNA of the 30S subunit of the bacterial ribosome, which prevents the attachment of amino acids to the elongating peptide chain. Spiramycin III has been shown to be active against a wide range of bacteria, including strains of Escherichia coli and Staphylococcus aureus. The levorotatory form is more potent than the dextrorotatory form and has a greater inhibitory effect on protein synthesis. Spiramycin III also has an inhibitory effect on inflammatory diseases such as arthritis and asthma. This drug binds to messenger RNA (mRNA) and blocks its access to ribosomes in order to prevent protein synthesis.

Formula: C₄₆H₇₈N₂O₁₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 899.12 g/mol

Ref: 3D-FS75020

Spiramycin III

CAS: 24916-52-7

Formula: C₄₆H₇₈N₂O₁₅

Molecular weight: 899.13

Ref: ST-EA-CP-S21010