CAS 249296-44-4

Varenicline

Description:

Varenicline is a prescription medication primarily used as an aid in smoking cessation. It acts as a partial agonist at nicotinic acetylcholine receptors, which helps to reduce withdrawal symptoms and cravings associated with nicotine addiction. The chemical formula of varenicline is C13H13ClN2, and it features a bicyclic structure that includes a pyridine and a pyrrolidine ring. This unique structure contributes to its pharmacological activity. Varenicline is typically administered orally and is known for its relatively favorable side effect profile compared to other smoking cessation aids. Common side effects may include nausea, insomnia, and vivid dreams, while more serious risks involve potential neuropsychiatric effects. The substance is metabolized primarily in the liver and has a half-life that allows for once or twice daily dosing. Due to its mechanism of action, varenicline not only helps individuals quit smoking but also may reduce the satisfaction derived from smoking if relapse occurs. As with any medication, it is important for users to consult healthcare professionals for personalized advice and monitoring during treatment.

Formula: C₁₃H₁₃N₃

InChI: InChI=1/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2

InChI key: InChIKey=JQSHBVHOMNKWFT-UHFFFAOYSA-N

SMILES: C1=2C(C3CC1CNC3)=CC=4C(C2)=NC=CN4

Synonyms:

• 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-
• Vareniclene
• Varenicline free base
• Varenicline
• 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine
• 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline
• Chantix
• 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine
• 6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-
• CP 526555
• Unii-W6hs99o8zo
• Varenicline base
• 10-Methano-6H-pyrazino[2
• (1R,12S)-5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2,4(9),5,7,10-pentaene
• 3-h][3]benzazepine
• CP 526555;CHAMPIX;CHANTIX;CP526555;CP-526555
• CS-861
• 10-tetrahydro-
• Varenicline Impurity

(1R,12S)-5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene

CAS: 249296-44-4

Formula: C₁₃H₁₃N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 211.2624

Ref: IN-DA002PWQ

Varenicline

CAS: 249296-44-4

Varenicline

Purity: ≥98%

Molecular weight: 211.26g/mol

Ref: 54-BUP10131

Varenicline

CAS: 249296-44-4

Formula: C₁₃H₁₃N₃

Color and Shape: Pale Yellow Solid

Molecular weight: 211.27

Ref: 4Z-V-251

Varenicline

Controlled Product

CAS: 249296-44-4

Formula: C₁₃H₁₃N₃

Color and Shape: Neat

Molecular weight: 211.262

Ref: TR-V215635

Varenicline

CAS: 249296-44-4

Partial agonist of α4β2 nicotinic receptors; acetylcholine receptor α7 agonist

Formula: C₁₃H₁₃N₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 211.26 g/mol

Ref: 3D-FT61475

Varenicline

CAS: 249296-44-4

Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.

Formula: C₁₃H₁₃N₃

Purity: 99.76%

Color and Shape: Solid

Molecular weight: 211.26

Ref: TM-T4246L