CAS 249537-73-3

H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh

Description:

The substance referred to as "H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-Oh" with the CAS number 249537-73-3 is a peptide, specifically a sequence of amino acids linked by peptide bonds. This compound features a variety of amino acids, including methionine (Met), alanine (Ala), glycine (Gly), proline (Pro), histidine (His), valine (Val), isoleucine (Ile), threonine (Thr), and glutamic acid (Glu). The presence of proline suggests structural rigidity, while the diverse side chains of the other amino acids contribute to its potential biological activity and interactions. The "H-" prefix indicates that the peptide is likely in its protected form, while the "Oh" at the end suggests the presence of a hydroxyl group, which may influence its solubility and reactivity. Peptides like this one can play significant roles in biological processes, including signaling, enzyme activity, and cellular communication, making them of interest in fields such as biochemistry and pharmacology.

NFAT Inhibitor

CAS: 249537-73-3

The flow of information from calcium-mobilizing receptors to nuclear factor of activated T cells (NFAT)-dependent genes is critically dependent on interaction between the phosphatase calcineurin and the transcription factor NFAT. The high-affinity calcineurin-binding peptide potently inhibited NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT. NFAT inhibitors may be useful in treating chronic ailments such as myocardial hypertrophy, allergy, arthritis, and autoimmune disease.

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purity: 98.2%

Color and Shape: White Powder

Molecular weight: 1683.95

Ref: 01-4034010

NFAT Inhibitor-1

CAS: 249537-73-3

Formula: C₇₅H₁₂₀N₂₀O₂₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1685.9411

Ref: IN-DA00BERD

NFAT Inhibitor

CAS: 249537-73-3

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Molecular weight: 1683.93

Ref: 7W-GL0293

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purity: 98.26%

Color and Shape: Solid

Molecular weight: 1683.93

Ref: TM-TP1015

NFAT Inhibitor

CAS: 249537-73-3

NFAT Inhibitor

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purity: 98% (Typical Value in Batch COA)

Color and Shape: white solid

Molecular weight: 1,797.95g/mol

Ref: 54-BISN0319

NFAT Inhibitor trifluoroacetate salt

CAS: 249537-73-3

NFAT Inhibitor trifluoroacetate salt H-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu (NFAT) is an inhibitor drug that has been shown to inhibit the nuclear factor of activated T cells (NFAT). NFAT is a transcriptional regulator that controls the expression of inflammatory genes in macrophages and other cell types. NFAT inhibitors have been shown to be effective for treating bowel diseases, such as ulcerative colitis and Crohn's disease, by inhibiting the activation of macrophages. NFAT inhibitors are also used in vitro as a tool for studying cellular signaling pathways. The most common type of NFAT inhibitor is fluconazole, which blocks calcineurin activity and prevents the activation of NFAT. However, other types of inhibitors are being developed, including mmp9 activity or

Formula: C₇₅H₁₁₈N₂₀O₂₂S

Purity: Min. 95%

Molecular weight: 1,683.93 g/mol

Ref: 3D-FN109384