Z-Gly-Leu-Ala-OH, also known as Z-Glycine-Leucine-Alanine, is a synthetic peptide that consists of three amino acids: glycine, leucine, and alanine, with a protective Z (benzyloxycarbonyl) group on the amino terminus. This protective group enhances the stability and solubility of the peptide during synthesis and storage. The compound is typically used in biochemical research and pharmaceutical applications, particularly in studies related to peptide synthesis, protein interactions, and drug development. Its structure allows for various conformations, influencing its biological activity and interactions with other molecules. Z-Gly-Leu-Ala-OH is soluble in polar solvents, such as water and dimethyl sulfoxide (DMSO), and is generally stable under standard laboratory conditions. However, like many peptides, it may be sensitive to extreme pH levels and temperature. The CAS number 24960-20-1 uniquely identifies this compound in chemical databases, facilitating its recognition and study in scientific literature.

Z-Gly-Leu-Ala-OH

24960-20-1: Z-Gly-Leu-Ala-OH, also known as Z-Glycine-Leucine-Alanine, is a synthetic peptide that consists of three amino acids: glycine, leucine, and alanine, with a protective Z (benzyloxycarbonyl) group on the amino terminus. This protective group enhances the stability and solubility of the peptide during synthesis and storage. The compound is typically used in biochemical research and pharmaceutical applications, particularly in studies related to peptide synthesis, protein interactions, and drug development. Its structure allows for various conformations, influencing its biological activity and interactions with other molecules. Z-Gly-Leu-Ala-OH is soluble in polar solvents, such as water and dimethyl sulfoxide (DMSO), and is generally stable under standard laboratory conditions. However, like many peptides, it may be sensitive to extreme pH levels and temperature. The CAS number 24960-20-1 uniquely identifies this compound in chemical databases, facilitating its recognition and study in scientific literature.

The peptide Z-Gly-Leu-Ala-OH is a reactive substance that is generated by the cleavage of casein kinase II. The peptide has been shown to have cytotoxic effects on Hodgkin's lymphoma cells, and also induces apoptosis in these cells. This peptide binds to mitochondria and causes mitochondrial damage, as well as generating reactive oxygen species (ROS) in the cell. ROS generation is dependent on oxygen species.

CAS 24960-20-1

Z-Gly-Leu-Ala-OH

Z-Gly-Leu-Ala-OH

Ref: 3D-FG111551