CAS 2498-41-1

5-Methyl dCMP

Description:

5-Methyl dCMP, or 5-methyl-2'-deoxycytidine monophosphate, is a nucleoside monophosphate that plays a significant role in the structure of DNA. It is a derivative of deoxycytidine, where a methyl group is attached to the fifth carbon of the pyrimidine ring. This modification can influence gene expression and is often studied in the context of epigenetics, particularly in relation to DNA methylation patterns. The presence of the methyl group can affect the stability of the DNA molecule and its interactions with proteins, thereby impacting cellular processes such as replication and transcription. 5-Methyl dCMP is also involved in various biochemical pathways, including those related to nucleotide metabolism. Its CAS number, 2498-41-1, is used for identification in chemical databases. As a chemical entity, it is typically characterized by its molecular formula, which reflects its constituent atoms, and its physical properties, which may include solubility and stability under various conditions. Understanding its characteristics is essential for research in molecular biology and genetics.

Formula: C₁₀H₁₆N₃O₇P

InChI: InChI=1/C10H16N3O7P/c1-5-3-13(10(15)12-9(5)11)8-2-6(14)7(20-8)4-19-21(16,17)18/h3,6-8,14H,2,4H2,1H3,(H2,11,12,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

InChI key: InChIKey=RGDVNLHBCKWZDA-XLPZGREQSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)C2)C=C(C)C(N)=N1

Synonyms:

• 2'-Deoxy-5-Methylcytidine 5'-(Dihydrogen Phosphate)
• 2'-Deoxy-5-methylcytidine 5'-monophosphate
• 2′-Deoxy-5-methyl-5′-cytidylic acid
• 2′-Deoxy-5-methylcytidine 5′-phosphate
• 5-Methyl dCMP
• 5-Methyl-deoxycytidylic acid
• 5-Methyldeoxycytidine monophosphate
• 5-Methyldeoxycytidylic acid
• 5′-Cytidylic acid, 2′-deoxy-5-methyl-
• Cytidine, 2′-deoxy-5-methyl-, 5′-(dihydrogen phosphate)
• Cytidine, 2′-deoxy-5-methyl-, 5′-phosphate
• Deoxy-5-methylcytidylic acid
• 5-methyl-2'-deoxycytidine 5'-monophosphate
• 2''-Deoxy-5-methylcytidine-5''-phosphoric acid
• 5-Methyldeoxycytidine-5'-monophosphoric acid
• 5-Methyl-2'-deoxy-5'-cytidylic acid
• 5-mdCMP
• 5-MedCTP
• 5-MedCT

5'-Cytidylic acid, 2'-deoxy-5-methyl-

CAS: 2498-41-1

Formula: C₁₀H₁₆N₃O₇P

Purity: 95%

Color and Shape: Solid

Molecular weight: 321.2237

Ref: IN-DA002Q2V

5-Methyl-2'-deoxycytidine 5'-monophosphate

CAS: 2498-41-1

5-Methyl-2'-deoxycytidine 5'-monophosphate

Purity: 95%

Molecular weight: 321.23g/mol

Ref: 54-OR1070343

2''-Deoxy-5-methylcytidine-5''-monophosphate disodium salt

CAS: 2498-41-1

Formula: C₁₀H₁₄N₃O₇PNa₂

Purity: (HPLC) ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 365.19

Ref: 7W-GN7411

2'-Deoxy-5-methylcytidine-5'-monophosphate disodium

CAS: 2498-41-1

2'-Deoxy-5-methylcytidine-5'-monophosphate disodium (2D5MCP) is a nucleoside analog that inhibits the synthesis of DNA. It is used in the treatment of cervical cancer and other cancers that are dependent on DNA synthesis. 2D5MCP works by binding to and inhibiting the activity of an enzyme called DNA polymerase, which is needed for DNA replication. This drug also has been shown to inhibit fatty acid synthase enzymes and surface glycoprotein enzymes, which may be responsible for its anti-cancer effects. 2D5MCP has been shown to have an effective dose range between 50 and 150 mg/kg, with no significant side effects seen at doses up to 300 mg/kg. 2D5MCP does not bind to plasma proteins or erythrocytes, so it can be administered intravenously without risk of tissue damage caused by osmotic lysis.

Formula: C₁₀H₁₄N₃O₇PNa₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 365.19 g/mol

Ref: 3D-ND10012

((2R,3S,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

CAS: 2498-41-1

Purity: 95%

Molecular weight: 321.2260132

Ref: 10-F772402