CAS 249921-19-5: Anamorelin

Description: Anamorelin is a synthetic small molecule classified as a ghrelin receptor agonist, primarily developed for its potential use in treating cachexia, a condition characterized by severe weight loss and muscle wasting often associated with chronic illnesses such as cancer. Its mechanism of action involves stimulating the growth hormone secretagogue receptor, which mimics the action of ghrelin, a hormone that promotes appetite and increases food intake. Anamorelin has been shown to enhance appetite and improve body weight in clinical settings. The substance is typically administered orally and has undergone various clinical trials to assess its efficacy and safety profile. In terms of chemical characteristics, Anamorelin has a specific molecular structure that contributes to its biological activity, and it is subject to standard pharmacological evaluations to determine its therapeutic potential and side effects. As with any pharmaceutical compound, its use should be guided by healthcare professionals, considering the individual patient's condition and overall treatment plan.

Formula: C₃₁H₄₂N₆O₃

InChI: InChI=1S/C31H42N6O3/c1-30(2,32)28(39)34-26(18-23-20-33-25-15-10-9-14-24(23)25)27(38)37-17-11-16-31(21-37,29(40)36(5)35(3)4)19-22-12-7-6-8-13-22/h6-10,12-15,20,26,33H,11,16-19,21,32H2,1-5H3,(H,34,39)/t26-,31-/m1/s1

InChI key: InChIKey=VQPFSIRUEPQQPP-MXBOTTGLSA-N

SMILES: O=C(NC(C(=O)N1CCCC(C(=O)N(N(C)C)C)(CC=2C=CC=CC2)C1)CC3=CNC=4C=CC=CC43)C(N)(C)C

Synonyms:

• (3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
• 3-Piperidinecarboxylic acid, 1-(2-methylalanyl-<span class="text-smallcaps">D</span>-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-
• 3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)-
• Rc 1291
• Anamorelin
• 3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-

3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)-

CAS: 249921-19-5

• Formula: C₃₁H₄₂N₆O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 546.7036

Anamorelin

CAS: 249921-19-5

Anamorelin (ONO-7643) is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).

• Formula: C₃₁H₄₂N₆O₃
• Purity: 99.35% - 99.88%
• Color and Shape: Solid
• Molecular weight: 546.7

Anamorelin

CAS: 249921-19-5

• Formula: C₃₁H₄₂N₆O₃
• Molecular weight: 546.72

Anamorelin

CAS: 249921-19-5

Applications Anamorelin functions as a novel therapeutic options for cachexia and sarcopenia. Cancer cachexia and …

• Formula: C₃₁H₄₂N₆O₃
• Color and Shape: White To Off-White
• Molecular weight: 546.70

Anamorelin Dihydrochloride

CAS: 249921-19-5

Applications Anamorelin is a novel non-peptidic ghrelin mimetic and growth hormone secratogogue. References Garcia, Jose …

• Formula: C₃₁H₄₂N₆O₃
• Color and Shape: Neat
• Molecular weight: 546.70

Anamorelin-d6

CAS: 249921-19-5

Applications Anamorelin-d6 is labelled Anamorelin (A617045) which is a novel non-peptidic ghrelin mimetic and growth …

• Formula: C₃₁D₆H₃₆N₆O₃
• Color and Shape: Neat
• Molecular weight: 552.741

Anamorelin

CAS: 249921-19-5

Please enquire for more information about Anamorelin including the price, delivery time and more detailed …

• Formula: C₃₁H₄₂N₆O₃
• Purity: Min. 95%
• Molecular weight: 546.7 g/mol