CAS 2500-80-3

9-(4-thiopentofuranosyl)-9H-purin-6-amine

Description:

9-(4-Thiopentofuranosyl)-9H-purin-6-amine, also known by its CAS number 2500-80-3, is a purine nucleoside analog characterized by the presence of a thiopentofuranosyl moiety attached to a purine base. This compound features a 9H-purine structure, which is a bicyclic aromatic compound consisting of fused imidazole and pyrimidine rings, and it is substituted at the 6-position with an amine group. The thiopentofuranosyl component introduces a sulfur atom into the sugar moiety, which can influence the compound's biological activity and stability. Such modifications often enhance the compound's potential as an antiviral or anticancer agent by altering its interaction with nucleic acid synthesis pathways. The unique structural features of this compound may also affect its solubility, permeability, and overall pharmacokinetics. As a nucleoside analog, it may mimic natural nucleosides, potentially interfering with nucleic acid metabolism in various biological systems. Further studies would be necessary to elucidate its specific biological activities and therapeutic applications.

Formula: C₁₀H₁₃N₅O₃S

InChI: InChI=1/C10H13N5O3S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)

SMILES: C(C1C(C(C(n2cnc3c(N)ncnc23)S1)O)O)O

4′-Thioadenosine

CAS: 2500-80-3

Formula: C₁₀H₁₃N₅O₃S

Color and Shape: Solid

Molecular weight: 283.3069

Ref: IN-DA002Q67

4'-Thioadenosine

CAS: 2500-80-3

4'-Thioadenosine is a Nucleoside Derivative - Thio-nucleoside.

Formula: C₁₀H₁₃N₅O₃S

Color and Shape: Solid

Molecular weight: 283.31

Ref: TM-TNU0183

4'-Thioadenosine

CAS: 2500-80-3

4'-Thioadenosine is a nucleoside that has been shown to inhibit the growth of leukemia cells by binding to adenosine receptors. It is also able to inhibit the activity of the mammalian phosphodiesterase PDE4, which is responsible for hydrolyzing cAMP. The cellular effects of 4'-thioadenosine can be seen in HL-60 human cells, and this drug has also shown promising results in animal models of kidney fibrosis and liver cirrhosis. 4'-Thioadenosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Formula: C₁₀H₁₃N₅O₃S

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 283.31 g/mol

Ref: 3D-NT162617