CAS 2504911-73-1

2,6-Piperidinedione, 3-[5-[4-[[1-[4-[(3S,4R)-3,4-dihydro-7-hydroxy-3-phenyl-2H-1-benzopyran-4-yl]-2-fluorophenyl]-4-piperidinyl]methyl]-1-piperazinyl]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (3S)-

Description:

2,6-Piperidinedione, 3-[5-[4-[[1-[4-[(3S,4R)-3,4-dihydro-7-hydroxy-3-phenyl-2H-1-benzopyran-4-yl]-2-fluorophenyl]-4-piperidinyl]methyl]-1-piperazinyl]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (3S)- (CAS 2504911-73-1) is a complex organic compound characterized by its multi-cyclic structure and various functional groups. This substance features a piperidine ring, which is known for its basic properties and ability to form hydrogen bonds, contributing to its potential biological activity. The presence of a benzopyran moiety suggests possible interactions with biological targets, particularly in medicinal chemistry. Additionally, the compound contains multiple chiral centers, indicating stereochemical complexity that may influence its pharmacological properties. The fluorophenyl and piperazinyl groups enhance its lipophilicity and may improve its ability to cross biological membranes. Overall, this compound's intricate structure and diverse functional groups suggest potential applications in drug development, particularly in areas targeting neurological or oncological conditions. However, detailed studies would be necessary to fully elucidate its properties and biological activities.

Formula: C₄₄H₄₆FN₅O₅

Synonyms:

• 2,6-Piperidinedione, 3-[5-[4-[[1-[4-[(3S,4R)-3,4-dihydro-7-hydroxy-3-phenyl-2H-1-benzopyran-4-yl]-2-fluorophenyl]-4-piperidinyl]methyl]-1-piperazinyl]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, (3S)-

PROTAC ER Degrader-14

CAS: 2504911-73-1

PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor/ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.

Formula: C₄₄H₄₆FN₅O₅

Color and Shape: Solid

Molecular weight: 743.865

Ref: TM-T204554