CAS 25055-86-1

3-Methyl-3H-diazirine-3-propanoic acid

Description:

3-Methyl-3H-diazirine-3-propanoic acid is a diazirine derivative known for its unique structural and chemical properties. It features a diazirine ring, which is a five-membered heterocyclic compound containing two adjacent nitrogen atoms. This compound is characterized by its ability to undergo photochemical reactions, particularly upon exposure to ultraviolet light, leading to the formation of reactive intermediates that can covalently bond with nearby molecules. This property makes it valuable in various applications, including bioconjugation and labeling in biochemical research. The presence of the propanoic acid moiety contributes to its solubility in polar solvents and enhances its reactivity. Additionally, the methyl group on the diazirine ring can influence its steric and electronic properties, affecting its reactivity and interaction with other chemical species. Overall, 3-Methyl-3H-diazirine-3-propanoic acid is a versatile compound with significant utility in chemical biology and materials science.

Formula: C₅H₈N₂O₂

InChI: InChI=1S/C5H8N2O2/c1-5(6-7-5)3-2-4(8)9/h2-3H2,1H3,(H,8,9)

InChI key: InChIKey=DSOGRJSLWCABBW-UHFFFAOYSA-N

SMILES: C(CC(O)=O)C1(C)N=N1

Synonyms:

• 3H-Diazirine-3-propionic acid, 3-methyl-
• 3-Methyl-3H-diazirine-3-propanoic acid
• 3-(3-Methyldiazirin-3-yl)propanoic acid
• 3-(3-Methyl-3H-diaziren-3-yl)propanoic acid
• 3H-Diazirine-3-propanoic acid, 3-methyl-
• 3-(3-Methyl-3H-diazirine-3-yl)propionic acid
• 3-Methyl-3H-diazirine-3-propionic acid
• 3-Methyl-diazirine-3-propanoic Acid
• Me-Diazirine-COOH
• 3-(3-methyl-3H-diazirin-3-yl)propanoic acid

3H-Diazirine-3-propanoic acid, 3-methyl-

CAS: 25055-86-1

Formula: C₅H₈N₂O₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 128.1292

Ref: IN-DA002QB0

3-(3-Methyl-3H-diazirin-3-yl)propanoic acid

CAS: 25055-86-1

3-(3-Methyl-3H-diazirin-3-yl)propanoic acid

Purity: 99%

Molecular weight: 128.13g/mol

Ref: 54-OR85612

3-Methyl-diazirine-3-propanoic Acid

Controlled Product

CAS: 25055-86-1

Stability Light Sensitive
Applications 3-Methyl-diazirine-3-propanoic Acid is a reagent used in crosslinking sugars and photoactivatable crosslinking.
References Tanaka, Y. et al.: J. Am. Chem. Soc., 130, 3278 (2008);

Formula: C₅H₈N₂O₂

Color and Shape: Neat

Molecular weight: 128.13

Ref: TR-M299550

3-(3-Methyl-3H-diazirine-3-yl)propionic acid

CAS: 25055-86-1

3-(3-Methyl-3H-diazirine-3-yl)propionic acid (3MDZ) is a fluorophore that can be used in cancer research. It has been shown to bind to the active site of human SIRT1 and inhibit its activity, which leads to cell death by deacylating histone H3. 3MDZ is also able to bind to carbenes, which are highly reactive molecules that have been implicated in aging and cancer. 3MDZ has shown chemopreventive effects against tumor formation and growth by binding to the carbenes and preventing them from forming reactive oxygen species. It can be used as a fluorescent probe for studying the interactions between carbenes and nucleic acids.

Formula: C₅H₈N₂O₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 128.13 g/mol

Ref: 3D-FM157144

3-(3-Methyl-3H-diazirin-3-yl)propanoic acid

CAS: 25055-86-1

Formula: C₅H₈N₂O₂

Purity: 98%

Color and Shape: Liquid, No data available.

Molecular weight: 128.131

Ref: 10-F545020