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CAS 2508-72-7

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Antazoline hydrochloride

Description:
Antazoline hydrochloride is a pharmaceutical compound primarily used as an antihistamine, particularly in the treatment of allergic conditions and as a topical agent in ophthalmology. It is classified as a first-generation antihistamine, which means it can cross the blood-brain barrier, potentially leading to sedative effects. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including eye drops. Antazoline hydrochloride acts by blocking H1 histamine receptors, thereby alleviating symptoms such as itching, redness, and swelling associated with allergic reactions. Its pharmacological profile includes anticholinergic properties, which can contribute to side effects like dry mouth and drowsiness. The compound is typically administered in controlled doses, and its use should be monitored due to potential interactions with other medications and the risk of central nervous system depression. Overall, Antazoline hydrochloride is a valuable agent in managing allergic responses, particularly in ocular applications.
Formula:C17H20ClN3
InChI:InChI=1/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19)/p+1
InChI key:InChIKey=SWKDMSRRIBZZAY-UHFFFAOYSA-N
SMILES:N(CC1=CC=CC=C1)(CC=2NCCN2)C3=CC=CC=C3.Cl
Synonyms:
  • 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, hydrochloride (1:1)
  • 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-, monohydrochloride
  • 2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride
  • 2-Imidazoline, 2-[(N-benzylanilino)methyl]-, monohydrochloride
  • 2-{[benzyl(phenyl)amino]methyl}-4,5-dihydro-1H-imidazol-3-ium
  • 5512M
  • Antastan
  • Antasten
  • Antazoline HCL
  • Antazoline chloride
  • See more synonyms
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