CAS 2508-79-4

Methyldopate hydrochloride

Description:

Methyldopate hydrochloride is a chemical compound that serves primarily as a medication in the treatment of hypertension. It is a derivative of the amino acid L-DOPA and functions as an agonist of the central nervous system. The substance is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly acidic pH. Methyldopate hydrochloride acts by stimulating alpha-2 adrenergic receptors, leading to a decrease in sympathetic outflow and a subsequent reduction in blood pressure. Its pharmacological effects include sedation and a reduction in heart rate, making it useful in managing certain cardiovascular conditions. The compound is usually administered via injection and is subject to careful dosage regulation due to its potent effects. As with many medications, potential side effects may include drowsiness, dry mouth, and orthostatic hypotension. Overall, Methyldopate hydrochloride is an important therapeutic agent in the field of cardiovascular medicine, particularly for patients with specific types of hypertension.

Formula: C₁₂H₁₇NO₄·ClH

InChI: InChI=1S/C12H17NO4.ClH/c1-3-17-11(16)12(2,13)7-8-4-5-9(14)10(15)6-8;/h4-6,14-15H,3,7,13H2,1-2H3;1H/t12-;/m0./s1

InChI key: InChIKey=QSRVZCCJDKYRRF-YDALLXLXSA-N

SMILES: C([C@](C(OCC)=O)(C)N)C1=CC(O)=C(O)C=C1.Cl

Synonyms:

• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-α-methyl-, ethyl ester, hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-α-methyl-, ethyl ester, hydrochloride (1:1)
• Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, ethyl ester, hydrochloride, (-)-
• Aldomet ester hydrochloride
• Ethyl Methyldopate Hydrochloride
• Methyldopa ethyl ester hydrochloride
• Methyldopate Hydrochloride
• ethyl 3-hydroxy-alpha-methyl-L-tyrosinate
• ethyl 3-hydroxy-alpha-methyl-L-tyrosinate hydrochloride (1:1)
• α-Methyl-<span class="text-smallcaps">L</span>-dopa ethyl ester hydrochloride
• α-Methyldopa ethyl ester hydrochloride
• L-Tyrosine, 3-hydroxy-α-methyl-, ethyl ester, hydrochloride (1:1)

Methyldopate Hydrochloride

CAS: 2508-79-4

Color and Shape: Neat

Ref: 61-FOR3150.00

Methyldopate hydrochloride

CAS: 2508-79-4

Methyldopate hydrochloride

Formula: C₁₂H₁₇NO₄HCl

Purity: 99.5%

Color and Shape: Off White Crystalline Powder

Molecular weight: 275.09244

Ref: 47-241

Methyldopate

CAS: 2508-79-4

Formula: C₁₂H₁₈ClNO₄

Molecular weight: 275.7286

Ref: IN-DA002QFK

Methyldopate

Controlled Product

CAS: 2508-79-4

Applications Methyldopate Hydrochloride is used in the successful treatment of murine neural blastoma. As well displays hypotensive effects.
References Chelmicka-Schorr, E.. et al.: Eur. J. Canc., 26, 969 (1980); Walson, P. et al.: J. Pharm. Exp. Ther., 196, 151 (1975);

Formula: C₁₂H₁₇NO₄·ClH

Color and Shape: Neat

Molecular weight: 275.73

Ref: TR-M303865

Methyldopate hydrochloride

CAS: 2508-79-4

Methyldopate HCl is an agent of antihypertensive.

Formula: C₁₂H₁₈ClNO₄

Color and Shape: Solid

Molecular weight: 275.73

Ref: TM-T20133

Methyldopate Hydrochloride (DISCONTINUED)

CAS: 2508-79-4, 5123-53-5

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₁₂H₁₇NO₄·ClH

Color and Shape: White Off-White Powder

Molecular weight: 275.09244

Ref: 45-1427005