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CAS 2508-89-6

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Duazomycin

Description:
Duazomycin, with the CAS number 2508-89-6, is a naturally occurring antibiotic that belongs to the class of compounds known as aminoglycosides. It is primarily derived from the fermentation of certain strains of Streptomyces bacteria. Duazomycin exhibits antibacterial properties, particularly against a range of Gram-positive and some Gram-negative bacteria, making it of interest in the field of medicinal chemistry and antibiotic development. The compound functions by inhibiting bacterial protein synthesis, which is crucial for bacterial growth and replication. Structurally, Duazomycin contains multiple amino sugar moieties, contributing to its solubility and interaction with bacterial ribosomes. Its therapeutic potential has been explored in various studies, although its clinical use may be limited due to resistance issues and the emergence of alternative antibiotics. As with many antibiotics, the development of resistance in target bacteria poses a significant challenge, necessitating ongoing research into its efficacy and potential applications in treating bacterial infections.
Formula:C8H11N3O4
InChI:InChI=1S/C8H11N3O4/c1-5(12)11-7(8(14)15)3-2-6(13)4-10-9/h4,7H,2-3H2,1H3,(H,11,12)(H,14,15)/t7-/m0/s1
InChI key:InChIKey=WBSWOKCKZUNHQV-ZETCQYMHSA-N
SMILES:[C@@H](CCC(C=[N+]=[N-])=O)(NC(C)=O)C(O)=O
Synonyms:
  • Norleucine, N-acetyl-6-diazo-5-oxo-, L-
  • Duazomycin A
  • L-Norleucine, N-acetyl-6-diazo-5-oxo-
  • N-Acetyl-6-diazo-5-oxo-L-norleucine
  • Norleucine, N-acetyl-6-diazo-5-oxo-
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