CAS 2511547-82-1

Butanedioic acid, compd. with (2S)-2-[(4R)-2-amino-4-[4-(2-cyclopropyl-2H-1,2,3-triazol-4-yl)phenyl]-4,5-dihydro-5-oxo-4-(3,3,3-trifluoro-2,2-dimethylpropyl)-1H-imidazol-1-yl]-2-[4-chloro-3-[1-(difluoromethyl)-1H-1,2,4-triazol-5-yl]phenyl]ethyl N-[1-(difluoromethyl)cyclopropyl]carbamate (1:1)

Description:

The chemical substance known as Butanedioic acid, in complex with a specific amino-imidazole derivative, is characterized by its intricate molecular structure, which includes multiple functional groups and stereocenters. This compound features a butanedioic acid moiety, which contributes to its acidity and potential for forming salts or esters. The presence of a cyclopropyl group and various triazole and phenyl rings suggests that the compound may exhibit significant biological activity, possibly as a pharmaceutical agent. The inclusion of trifluoromethyl and difluoromethyl groups indicates enhanced lipophilicity and metabolic stability, which are often desirable in drug design. Additionally, the compound's stereochemistry, particularly the (2S) and (4R) configurations, may influence its interaction with biological targets, affecting its efficacy and safety profile. Overall, this compound exemplifies the complexity often found in modern medicinal chemistry, where diverse structural features are engineered to optimize therapeutic potential.

Formula: C₃₉H₄₀ClF₇N₁₀O₇

Synonyms:

• Butanedioic acid, compd. with (2S)-2-[(4R)-2-amino-4-[4-(2-cyclopropyl-2H-1,2,3-triazol-4-yl)phenyl]-4,5-dihydro-5-oxo-4-(3,3,3-trifluoro-2,2-dimethylpropyl)-1H-imidazol-1-yl]-2-[4-chloro-3-[1-(difluoromethyl)-1H-1,2,4-triazol-5-yl]phenyl]ethyl N-[1-(difluoromethyl)cyclopropyl]carbamate (1:1)

HIV protease-IN-1

CAS: 2511547-82-1

HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1].

Formula: C₃₉H₄₀ClF₇N₁₀O₇

Color and Shape: Solid

Molecular weight: 929.24

Ref: TM-T74939