CAS 25122-56-9
:Clobetasone propionate
Description:
Clobetasone propionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatology for the treatment of various skin conditions, such as eczema and psoriasis. It is characterized by its potent glucocorticoid activity, which helps reduce inflammation and alleviate symptoms associated with skin disorders. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Clobetasone propionate has a relatively low potency compared to other corticosteroids, making it suitable for use in sensitive areas of the skin or for long-term management of chronic conditions. Its mechanism of action involves the inhibition of inflammatory mediators and the modulation of immune responses. The compound is generally well-tolerated, but potential side effects may include skin thinning, irritation, or allergic reactions with prolonged use. As with all corticosteroids, it is important to use clobetasone propionate under medical supervision to minimize risks and ensure effective treatment.
Formula:C25H30ClFO5
InChI:InChI=1S/C25H30ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-18H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,22-,23-,24-,25-/m0/s1
InChI key:InChIKey=VAUBWHIQMRKGBN-BHHHYXKXSA-N
SMILES:O(C(CC)=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)(C(=O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Synonyms:- Clobetasone propionate
- Clobetasone-17-propionate
- Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)-, (16β)-
- (16β)-21-Chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,11,20-trione
- Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, propionate
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Found 3 products.
Clobetasone 17-Propionate
CAS:Controlled Product<p>Impurity Clobetasone Butyrate EP Impurity H<br>Applications Clobetasone-17-propionate is derived from Clobetasol (Clobetasol Propionate EP Impurity G) (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)<br></p>Formula:C25H30ClFO5Color and Shape:NeatMolecular weight:464.95
