CAS 251356-32-8

PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 - CAS 251356-32-8 - Calbiochem

Description:

PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, commonly referred to as 5-Br SU6668, is a synthetic compound that functions primarily as a selective inhibitor of receptor tyrosine kinases, specifically targeting platelet-derived growth factor receptors (PDGFR) and vascular endothelial growth factor receptors (VEGFR2). This compound is notable for its potential therapeutic applications in oncology and vascular biology, as it can impede tumor growth and angiogenesis by blocking the signaling pathways associated with these receptors. The chemical structure of 5-Br SU6668 includes a bromine atom, which contributes to its biological activity and specificity. It is typically utilized in research settings to study the mechanisms of cancer progression and the role of angiogenesis in tumor development. As a small molecule inhibitor, it is characterized by its ability to modulate cellular signaling pathways, making it a valuable tool in drug discovery and development. Safety and handling precautions are essential when working with this compound, as with any chemical agent used in laboratory settings.

Formula: C₁₈H₁₇BrN₂O₃

Synonyms:

• 5 Br SU6668
• PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 - CAS 251356-32-8 - Calbiochem
• SU-9518
• 5BrSU6668
• SU9518
• SU 9518
• 5-Br-SU6668

SU9518

CAS: 251356-32-8

SU9518, a PDGFRα-specific tyrosine kinase inhibitor, hinders PVR in rabbit fibroblast and Müller cells.

Formula: C₁₈H₁₇BrN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 389.24

Ref: TM-T28877