CAS 25137-01-3

(-)-Ethyl nipecotate

Description:

(-)-Ethyl nipecotate is a chemical compound characterized by its chiral nature, belonging to the class of nipecotic acid derivatives. It is typically recognized for its role as a potential pharmacological agent, particularly in the context of neuropharmacology. The compound features an ethyl ester functional group, which contributes to its solubility and reactivity. (-)-Ethyl nipecotate is known to exhibit biological activity, particularly as a selective inhibitor of certain neurotransmitter transporters, which may influence its effects on the central nervous system. The stereochemistry of the compound is significant, as the specific enantiomer can lead to different biological activities and interactions. In terms of physical properties, it is generally a colorless to pale yellow liquid or solid, depending on its form and purity. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose risks if ingested or inhaled. Overall, (-)-Ethyl nipecotate is of interest in both synthetic organic chemistry and medicinal chemistry for its potential therapeutic applications.

Formula: C₈H₁₅NO₂

InChI: InChI=1S/C8H15NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h7,9H,2-6H2,1H3/t7-/m1/s1

InChI key: InChIKey=XIWBSOUNZWSFKU-SSDOTTSWSA-N

SMILES: C(OCC)(=O)[C@@H]1CCCNC1

Synonyms:

• (-)-Ethyl nipecotate
• (-)-Nipecotic acid ethyl ester
• (3R)-(-)-Ethyl nipecotate
• (3R)-3-Piperidinecarboxylic acid ethyl ester
• (R)-3-Piperidinecarboxylic acid ethyl ester
• (R)-Ethyl nipecotate
• (R)-Ethyl piperidine-3-carboxylate
• (R)-Nipecotic Acid Ethyl Ester
• 3-Piperidinecarboxylic acid, ethyl ester, (R)-
• 3-piperidinecarboxylic acid, ethyl ester, (3R)-
• Ethyl (3R)-piperidine-3-carboxylate
• Ethyl (3R)-piperidinecarboxylate
• Ethyl (R)-3-piperidinecarboxylate
• Ethyl (R)-nipecotate

Ethyl (R)-(-)-3-Piperidinecarboxylate

CAS: 25137-01-3

Formula: C₈H₁₅NO₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 157.21

Ref: 3B-N0655

(R)-Ethyl piperidine-3-carboxylate

CAS: 25137-01-3

Formula: C₈H₁₅NO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 157.2102

Ref: IN-DA003CB8

Ethyl (3R)-piperidine-3-carboxylate

CAS: 25137-01-3

Ethyl (3R)-piperidine-3-carboxylate

Formula: C₈H₁₅NO₂

Purity: ≥95%

Color and Shape: clear. faint yellow liquid

Molecular weight: 157.21g/mol

Ref: 54-OR8969

(R)-ETHYL NIPECOTATE

CAS: 25137-01-3

Formula: C₈H₁₅NO₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 157.213

Ref: 10-F053390

R-(-)-Ethyl nipecotate

CAS: 25137-01-3

R-(-)-Ethyl nipecotate is a chiral molecule that has been shown to inhibit serine proteases. The enantiopure form of this compound was found to be more potent in inhibiting the activity of inflammatory enzymes than the racemic mixture. R-(-)-Ethyl nipecotate also inhibits uptake of these enzymes, which may be due to its ability to inhibit membrane transport proteins. In addition, R-(-)-Ethyl nipecotate has been shown to have an inotropic effect on rat heart muscle and may act as an inhibitor of cholinergic receptors in rat striatal membranes. Chromatographic methods have been used to identify the presence of this substance in rat striatal membranes and acid complexes have been used for its purification.

Formula: C₈H₁₅NO₂

Purity: Min. 95%

Molecular weight: 157.21 g/mol

Ref: 3D-FE44423