CAS 25152-20-9

5'-amino-5'-deoxythymidine

Description:

5'-Amino-5'-deoxythymidine, also known as adenosine-5'-monophosphate (AMP) derivative, is a nucleoside analog characterized by the presence of an amino group at the 5' position of the deoxythymidine structure. This compound is notable for its role in biochemical research and potential therapeutic applications, particularly in the fields of molecular biology and pharmacology. It exhibits properties typical of nucleosides, including the ability to participate in hydrogen bonding and form base pairs, which is crucial for its function in nucleic acid synthesis and metabolism. The amino group enhances its reactivity and can influence its interaction with enzymes and other biomolecules. Additionally, 5'-amino-5'-deoxythymidine may exhibit varying solubility in different solvents, which can affect its bioavailability and efficacy in biological systems. Its CAS number, 25152-20-9, is a unique identifier that facilitates the cataloging and study of this compound in scientific literature and databases. Overall, this substance is of significant interest for its potential applications in genetic research and therapeutic development.

Formula: C₁₀H₁₅N₃O₄

InChI: InChI=1/C10H15N3O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4,11H2,1H3,(H,12,15,16)/t6?,7-,8-/m1/s1

SMILES: Cc1cn([C@H]2CC([C@@H](CO)O2)N)c(=O)nc1O

Synonyms:

• 5'-Amino-2',5'-dideoxythymidine
• 5-Addot
• Nsc 169339
• Thymidine, 5'-amino-5'-deoxy- (8CI)(9CI)
• 1-(5-amino-2,5-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 5'-Amino-5'-deoxythymidine

1-((2R,4S,5R)-5-(Aminomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 25152-20-9

Formula: C₁₀H₁₅N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 241.2438

Ref: IN-DA002QNU

5'-Amino-5'-deoxythymidine

CAS: 25152-20-9

5'-Amino-5'-deoxythymidine

Purity: ≥98%

Molecular weight: 241.24g/mol

Ref: 54-BUP21129

5''-Amino-5''-deoxythymidine

CAS: 25152-20-9

Formula: C₁₀H₁₅N₃O₄

Molecular weight: 241.24

Ref: 7W-GN4738

5'-Amino-5'-deoxythymidine

CAS: 25152-20-9

5'-Amino-5'-deoxythymidine is a thymidine derivative widely used in biochemical experiments and drug synthesis research.

Formula: C₁₀H₁₅N₃O₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 241.24

Ref: TM-TNU1251

5'-Amino-5'-deoxythymidine

CAS: 25152-20-9

5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.

Formula: C₁₀H₁₅N₃O₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 241.24 g/mol

Ref: 3D-NA06395