CAS 251565-85-2

Tesaglitazar

Description:

Tesaglitazar is a synthetic compound that belongs to the class of thiazolidinediones, which are primarily used in the management of type 2 diabetes. It functions as a dual agonist for peroxisome proliferator-activated receptors (PPARs), specifically PPAR-α and PPAR-γ, which play crucial roles in glucose and lipid metabolism. This dual action helps improve insulin sensitivity and lipid profiles, making it beneficial for patients with metabolic syndrome. Tesaglitazar is characterized by its ability to reduce blood glucose levels and improve overall metabolic health. The compound has been studied for its potential to address not only diabetes but also associated cardiovascular risks. Its chemical structure includes a thiazolidinedione moiety, which is essential for its biological activity. However, like many drugs in this class, it may have side effects, including weight gain and fluid retention, which necessitate careful patient monitoring. Overall, Tesaglitazar represents a promising therapeutic option in the landscape of diabetes management, although its clinical use may be subject to regulatory considerations and ongoing research.

Formula: C₂₀H₂₄O₇S

InChI: InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1

InChI key: InChIKey=CXGTZJYQWSUFET-IBGZPJMESA-N

SMILES: C([C@H](OCC)C(O)=O)C1=CC=C(OCCC2=CC=C(OS(C)(=O)=O)C=C2)C=C1

Synonyms:

• (2S)-2-Ethoxy-3-[4-(2-{4-[(Methylsulfonyl)Oxy]Phenyl}Ethoxy)Phenyl]Propanoic Acid
• (2S)-2-ethoxy-3-[4-(2-{4-[(methylsuIfonyl)oxy]phenyl}ethoxy)phenyl]propanoic acid
• (S)-2-Ethoxy-3-(4-(2-(4-Methylsulphonyloxyphenyl)Ethoxy)Phenyl)Propanoic Acid
• (S)-2-Ethoxy-3-(4-(4-((methylsulfonyl)oxy)phenethoxy)phenyl)propanoic acid
• (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
• (S)-2-Ethoxy-3-{4-[2-(4-Methanesulfonyloxy-Phenyl)-Ethoxy]-Phenyl}-Propionic Acid
• (S)-2-Ethoxy-3-{4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl}propionic acid
• (S)-2-ethoxy-3-[4-(2-{4-
• (S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxy-phenyl}ethoxy)phenyl]propanoic acid
• (αS)-α-Ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]benzenepropanoic acid
• AZ2
• Ar-H 039242
• Ar-H 039242Xx
• Az-242
• Benzenepropanoic acid, α-ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]-, (αS)-
• Galida
• Methanesulphonyloxyphenyl}Ethoxy)Phenyl]Propanoic Acid
• Tesaglitazar
• Tesaglitizar

Benzenepropanoic acid, α-ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]-, (αS)-

CAS: 251565-85-2

Formula: C₂₀H₂₄O₇S

Purity: 95%

Color and Shape: Solid

Molecular weight: 408.4654

Ref: IN-DA002QO8

(S)-2-Ethoxy-3-(4-(4-((Methylsulfonyl)Oxy)Phenethoxy)Phenyl)Propanoic Acid

CAS: 251565-85-2

(S)-2-Ethoxy-3-(4-(4-((Methylsulfonyl)Oxy)Phenethoxy)Phenyl)Propanoic Acid

Purity: 95%

Molecular weight: 408.47g/mol

Ref: 54-OR1023822

Tesaglitazar

CAS: 251565-85-2

Tesaglitazar

Purity: ≥98%

Molecular weight: 408.47g/mol

Ref: 54-BUP12821

Tesaglitazar

CAS: 251565-85-2

Formula: C₂₀H₂₄O₇S

Purity: ≥95%(HPLC)

Color and Shape: Solid

Molecular weight: 408.47

Ref: 10-F041388

Tesaglitazar

Controlled Product

CAS: 251565-85-2

Formula: C₂₀H₂₄O₇S

Color and Shape: Neat

Molecular weight: 408.47

Ref: TR-T136000

Tesaglitazar

CAS: 251565-85-2

Peroxisome proliferator–activated receptor (PPAR) α/γ agonist

Formula: C₂₀H₂₄O₇S

Purity: Min. 95%

Molecular weight: 408.47 g/mol

Ref: 3D-FT28046

Tesaglitazar

CAS: 251565-85-2

Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα

Formula: C₂₀H₂₄O₇S

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 408.47

Ref: TM-T17044