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CAS 251565-85-2

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Tesaglitazar

Description:
Tesaglitazar is a synthetic compound that belongs to the class of thiazolidinediones, which are primarily used in the management of type 2 diabetes. It functions as a dual agonist for peroxisome proliferator-activated receptors (PPARs), specifically PPAR-α and PPAR-γ, which play crucial roles in glucose and lipid metabolism. This dual action helps improve insulin sensitivity and lipid profiles, making it beneficial for patients with metabolic syndrome. Tesaglitazar is characterized by its ability to reduce blood glucose levels and improve overall metabolic health. The compound has been studied for its potential to address not only diabetes but also associated cardiovascular risks. Its chemical structure includes a thiazolidinedione moiety, which is essential for its biological activity. However, like many drugs in this class, it may have side effects, including weight gain and fluid retention, which necessitate careful patient monitoring. Overall, Tesaglitazar represents a promising therapeutic option in the landscape of diabetes management, although its clinical use may be subject to regulatory considerations and ongoing research.
Formula:C20H24O7S
InChI:InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1
InChI key:InChIKey=CXGTZJYQWSUFET-IBGZPJMESA-N
SMILES:C([C@H](OCC)C(O)=O)C1=CC=C(OCCC2=CC=C(OS(C)(=O)=O)C=C2)C=C1
Synonyms:
  • (2S)-2-Ethoxy-3-[4-(2-{4-[(Methylsulfonyl)Oxy]Phenyl}Ethoxy)Phenyl]Propanoic Acid
  • (2S)-2-ethoxy-3-[4-(2-{4-[(methylsuIfonyl)oxy]phenyl}ethoxy)phenyl]propanoic acid
  • (S)-2-Ethoxy-3-(4-(2-(4-Methylsulphonyloxyphenyl)Ethoxy)Phenyl)Propanoic Acid
  • (S)-2-Ethoxy-3-(4-(4-((methylsulfonyl)oxy)phenethoxy)phenyl)propanoic acid
  • (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
  • (S)-2-Ethoxy-3-{4-[2-(4-Methanesulfonyloxy-Phenyl)-Ethoxy]-Phenyl}-Propionic Acid
  • (S)-2-Ethoxy-3-{4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl}propionic acid
  • (S)-2-ethoxy-3-[4-(2-{4-
  • (S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxy-phenyl}ethoxy)phenyl]propanoic acid
  • (αS)-α-Ethoxy-4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]benzenepropanoic acid
  • See more synonyms
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