CAS 251647-49-1

N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-(2-methoxyethyl)cytidine

Description:

N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-(2-methoxyethyl)cytidine is a synthetic nucleoside derivative characterized by its complex structure, which includes a benzoyl group and multiple methoxyphenyl substituents. This compound is designed to enhance the stability and bioavailability of nucleosides, making it of interest in pharmaceutical research, particularly in the development of antiviral and anticancer agents. The presence of methoxy groups typically increases lipophilicity, potentially improving cellular uptake. Additionally, the modifications at the 2′ and 5′ positions of the cytidine moiety can influence the compound's interaction with nucleic acid targets and enzymes, affecting its biological activity. The compound's CAS number, 251647-49-1, allows for precise identification in chemical databases. Overall, this substance exemplifies the strategic design of nucleoside analogs to optimize therapeutic efficacy while minimizing degradation and resistance in biological systems.

Formula: C₄₀H₄₁N₃O₉

InChI: InChI=1S/C40H41N3O9/c1-47-24-25-50-36-35(44)33(52-38(36)43-23-22-34(42-39(43)46)41-37(45)27-10-6-4-7-11-27)26-51-40(28-12-8-5-9-13-28,29-14-18-31(48-2)19-15-29)30-16-20-32(49-3)21-17-30/h4-23,33,35-36,38,44H,24-26H2,1-3H3,(H,41,42,45,46)/t33-,35-,36-,38-/m1/s1

InChI key: InChIKey=PRAZQDMVAGLVKR-XHOUGWTJSA-N

SMILES: C(OC[C@H]1O[C@H]([C@H](OCCOC)[C@@H]1O)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Synonyms:

• N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)cytidine
• N-benzoyl-5'-O-DmTr-2'-O-(2-methoxyethyl)-Cytidine
• Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-(2-methoxyethyl)-

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-

CAS: 251647-49-1

Formula: C₄₀H₄₁N₃O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 707.7682

Ref: IN-DA002QPO

N-(1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Hydroxy-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)-2-Oxo-1,2-Dihydropyrimidin-4-Yl)Benzamide

CAS: 251647-49-1

N-(1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Hydroxy-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)-2-Oxo-1,2-Dihydropyrimidin-4-Yl)Benzamide

Purity: 97%

Molecular weight: 707.77g/mol

Ref: 54-OR1013936

N-(1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

CAS: 251647-49-1

Purity: 97%

Molecular weight: 707.780029296875

Ref: 10-F603246

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine

CAS: 251647-49-1

Nucleoside Derivatives - 2’-Modified nucleosides; Protected nucleosides w/NH2/OH open

Formula: C₄₀H₄₁N₃O₉

Color and Shape: Solid

Molecular weight: 707.77

Ref: TM-TNU1239

N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine

CAS: 251647-49-1

N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine is a novel ribonucleotide that has been shown to inhibit the growth of cancer cells. It has been synthesized in high purity and quality, with a high phosphoramidite content, and is available in various quantities. This product is an activator of DNA polymerase and can be used as a monophosphate or diphosphate precursor for nucleic acid synthesis. It has antiviral properties, and may be useful in the treatment of HIV infection.

Formula: C₄₀H₄₁N₃O₉

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 707.77 g/mol

Ref: 3D-NB36301