![Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoeth…](https://static.cymitquimica.com/cas-image/thumb-webp/382986-adenosine-n-benzoyl-5-o-bis-4-methoxyphenyl-phenylmethyl-2-o-2-methoxyethyl-3-2-cyanoethyl-bis-1-methylethyl-phosphoramidite.webp)
CAS 251647-53-7
:Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Description:
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a modified adenosine structure, which includes various functional groups such as benzoyl and methoxyphenyl moieties, enhancing its reactivity and solubility. The presence of phosphoramidite functionality allows for its use in automated DNA synthesis, facilitating the incorporation of modified nucleotides into oligonucleotide sequences. The compound's unique structure contributes to its stability and efficiency in biochemical applications, making it valuable for research in molecular biology, genetic engineering, and therapeutic development. Its CAS number, 251647-53-7, serves as a unique identifier for regulatory and commercial purposes, ensuring precise communication regarding this specific chemical entity. Overall, this compound exemplifies the intricate design often employed in the development of nucleic acid analogs for advanced scientific applications.
Formula:C50H58N7O9P
InChI:InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-44-42(31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39)65-49(45(44)62-30-29-59-5)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1
InChI key:VPBYBQBHLYRLHG-HDMAWCRFSA-N
SMILES:CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
Synonyms:- DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.
DMT-2'-O-MOE-rA(Bz) Phosphoramidite
CAS:Formula:C50H58N7O9PPurity:>95.0%(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:932.032'-MOE Bz A β-Cyanoethyl Phosphoramidite
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C50H58N7O9PColor and Shape:White Off-White PowderMolecular weight:931.403362'-O-Moe-A(Bz)-3'-Phosphoramidite
CAS:2'-O-Moe-A(Bz)-3'-PhosphoramiditeFormula:C50H58N7O9PPurity:98%Molecular weight:932.01(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
CAS:Formula:C50H58N7O9PPurity:97.0%Color and Shape:SolidMolecular weight:932.01082'-O-MOE-A(Bz)-3'-phosphoramidite
CAS:2'-O-MOE-A(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite;Nucleoside Derivative - 2'-Modified nucleoside;.Formula:C50H58N7O9PColor and Shape:SolidMolecular weight:932.011DMT-2'-O-MOE-rA(Bz) phosphoramidite
CAS:(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramiditeFormula:C50H58N7O9PPurity:97.0%Molecular weight:932.01N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
CAS:Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides containing 2’-O-(2-methoxyethyl) adenosine nucleoside units. Using a chemical approach rather than an enzymatic one allows custom-made oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with an appropriate alcohol in the presence of an azole catalyst such as imidazole or 1H-tetrazole. N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite has been used in the synthesis of 2’-modified oligonucleotides as protein binding modulators.Formula:C50H58N7O9PPurity:Min. 95%Color and Shape:PowderMolecular weight:932.01 g/mol
