CAS 2519823-34-6

Acetamide, N-[7-[(3R)-3-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-1-piperidinyl]heptyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Description:

Acetamide, N-[7-[(3R)-3-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-1-piperidinyl]heptyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- (CAS 2519823-34-6) is a complex organic compound characterized by its multi-functional structure, which includes amide, piperidine, and pyrimidine moieties. This compound exhibits properties typical of amides, such as moderate solubility in polar solvents and potential for hydrogen bonding due to the presence of the amide functional group. The presence of various substituents, including a sulfonyl group and a chloro group, suggests that it may exhibit biological activity, potentially as a pharmaceutical agent. The intricate arrangement of its functional groups may influence its reactivity and interaction with biological targets. Additionally, the compound's molecular weight and structural complexity indicate that it may require specific conditions for synthesis and purification. Overall, this compound represents a significant interest in medicinal chemistry, particularly in the development of targeted therapies.

Formula: C₄₀H₄₉ClN₈O₈S

Synonyms:

• Acetamide, N-[7-[(3R)-3-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-1-piperidinyl]heptyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
• BSJ-4-116

BSJ-4-116

CAS: 2519823-34-6

Formula: C₄₀H₄₉ClN₈O₈S

Purity: %

Color and Shape: Solid

Molecular weight: 837.3839

Ref: IN-DA01V2M1

BSJ-4-116

CAS: 2519823-34-6

BSJ-4-116

Purity: ≥98%

Molecular weight: 837.38g/mol

Ref: 54-BUP03184

N-(7-((R)-3-((5-Chloro-4-((2-(Isopropylsulfonyl)Phenyl)Amino)Pyrimidin-2-Yl)Amino)Piperidin-1-Yl)Heptyl)-2-((2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-4-Yl)Oxy)Acetamide

CAS: 2519823-34-6

N-(7-((R)-3-((5-Chloro-4-((2-(Isopropylsulfonyl)Phenyl)Amino)Pyrimidin-2-Yl)Amino)Piperidin-1-Yl)Heptyl)-2-((2-(2,6-Dioxopiperidin-3-Yl)-1,3-Dioxoisoindolin-4-Yl)Oxy)Acetamide

Purity: 98+%

Molecular weight: 837.38g/mol

Ref: 54-OR1023858

BSJ-4-116

CAS: 2519823-34-6

BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.

Formula: C₄₀H₄₉ClN₈O₈S

Purity: 99.09%

Color and Shape: Solid

Molecular weight: 837.38

Ref: TM-T9117

BSJ-4-116

CAS: 2519823-34-6

BSJ-4-116 is a small molecule that has been shown to activate the GABA receptor. It has been shown to have high affinity for the GABA receptor, with a Kd of 1.2 nM in the rat cortex. BSJ-4-116 also has high purity, with a maximum of 0.5% impurities in the drug substance and no detectable impurities in the product. BSJ-4-116 has been shown to be an inhibitor of ion channels by preventing chloride ions from entering into cells and causing an influx of positive ions across the membrane, which may lead to hyperpolarization of neurons and inhibition of neuronal activity.

Formula: C₄₀H₄₉ClN₈O₈S

Purity: Min. 95%

Molecular weight: 837.40 g/mol

Ref: 3D-UAE82334