CAS 252049-10-8

Fmoc-N',N'-dimethyl-L-lysine hydrochloride

Description:

Fmoc-N',N'-dimethyl-L-lysine hydrochloride is a derivative of the amino acid lysine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino group and two methyl groups on the nitrogen atoms of the side chain. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis, due to its ability to protect the amino group while allowing for further reactions. The Fmoc group can be removed under basic conditions, facilitating the sequential addition of amino acids. The hydrochloride form indicates that the compound is a salt, which enhances its solubility in polar solvents, making it suitable for various biochemical applications. The presence of the dimethyl groups contributes to the steric bulk of the side chain, influencing the conformation and reactivity of the resulting peptides. Overall, Fmoc-N',N'-dimethyl-L-lysine hydrochloride is a valuable building block in the synthesis of complex peptides and proteins in research and pharmaceutical contexts.

Formula: C₂₃H₂₈N₂O₄HCl

InChI: InChI=1S/C23H28N2O4.ClH/c1-25(2)14-8-7-13-21(22(26)27)24-23(28)29-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20;/h3-6,9-12,20-21H,7-8,13-15H2,1-2H3,(H,24,28)(H,26,27);1H/t21-;/m0./s1

InChI key: SJFAFKDBWNFBCC-BOXHHOBZSA-N

SMILES: CN(C)CCCC[C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13.Cl

Synonyms:

• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N',N'-dimethyl-L-lysine hydrochloride
• Fmoc-Lys(Me)2-OH HCl
• Fmoc-Lys(Me2)-OH.HCL
• Fmoc-Lys(Me)2-OH・HCl

Fmoc-Lys(Me)₂-OH · HCl

CAS: 252049-10-8

CAS-Number (net): 378802-00-7.

Formula: C₂₃H₂₈N₂O₄·HCl

Purity: 98.63%

Color and Shape: Whitish Crystalline Powder

Molecular weight: 432.95

Ref: 01-4028600

Fmoc-Lys(Me)2-OH · HCl

CAS: 252049-10-8

Fmoc-Lys(Me)2-OH · HCl

Formula: C₂₃H₂₈N₂O₄·ClH

Purity: 98%

Molecular weight: 432.94035

Ref: 54-BIBA1024

Fmoc-L-Lys(Me2)-OH*HCl

CAS: 252049-10-8

Formula: C₂₃H₂₉ClN₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 432.9404

Ref: IN-DA002QWZ

Fmoc-Lys(Me)2-OH·HCl

CAS: 252049-10-8

Fmoc-Lys(Me2)-OH.HCl

Formula: C₂₃H₂₉ClN₂O₄

Purity: 98%

Molecular weight: 432.94

Ref: IN-DG182316

FMOC-Lys(Me)2-OH HCl

CAS: 252049-10-8

Formula: C₂₃H₂₉ClN₂O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 432.95

Ref: 10-F044807

(S)-N-Fmoc-N6,N6-dimethyl-L-lysine Hydrochloride

Controlled Product

CAS: 252049-10-8

Applications Di-Me L-lysine derivative. The methylation of lysine in histone tails is a common posttranslational modification that functions in histone-regulated chromatin condensation, with binding of methylated lysine occurring in aromatic pockets on chromodomain proteins.
References Schreiber, G., et al.: J. Mol. Biol., 248, 478 (1995), Jacobs, S., et al.: Science, 295, 2080 (2002), Tatko, C., et al.: Protein Sci., 12, 2443 (2003),

Formula: C₂₃H₂₈N₂O₄·ClH

Color and Shape: Neat

Molecular weight: 432.94

Ref: TR-F648400