CAS 252049-14-2

4-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine

Description:

4-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine, commonly referred to as a protected amino acid, is characterized by its complex structure that includes a bulky tert-butyl group and a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis, due to its stability and ease of removal of the Fmoc group under mild basic conditions. The presence of the D-phenylalanine moiety contributes to its unique stereochemistry, which can influence the folding and activity of peptides in which it is incorporated. The compound is generally soluble in organic solvents like dimethyl sulfoxide (DMSO) and dichloromethane, but its solubility in water is limited. Its molecular structure allows for specific interactions in biological systems, making it a valuable building block in the development of pharmaceuticals and bioconjugates. Safety data should be consulted for handling, as with all chemical substances, to ensure proper laboratory practices.

Formula: C₂₈H₂₉NO₄

InChI: InChI=1S/C28H29NO4/c1-28(2,3)19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m1/s1

InChI key: InChIKey=OKEORFXNCSRZFL-RUZDIDTESA-N

SMILES: C(OC(N[C@H](CC1=CC=C(C(C)(C)C)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• 4-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
• 4-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine
• <span class="text-smallcaps">D</span>-Phenylalanine, 4-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-4-tert-butyl-D-phenylalanine
• Fmoc-D-4-tetr-Butylphenylalanine
• Fmoc-D-Phe(4-tBu)-OH
• D-Phenylalanine, 4-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• 4-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine

Fmoc-D-4-tert-butyl-Phe

CAS: 252049-14-2

Formula: C₂₈H₂₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 443.5342

Ref: IN-DA002QWY

4-tert-Butyl-D-phenylalanine, N-FMOC protected

CAS: 252049-14-2

4-tert-Butyl-D-phenylalanine, N-FMOC protected

Purity: 98%

Ref: 54-OR14625

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butyl)phenyl)propanoic acid

CAS: 252049-14-2

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butyl)phenyl)propanoic acid

Purity: 98%

Molecular weight: 443.53g/mol

Ref: 54-OR76049

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butyl)phenyl)propanoic acid

CAS: 252049-14-2

Purity: 98%

Molecular weight: 443.5429993

Ref: 10-F695038