CAS 252049-16-4

Fmoc-His(3-Me)-OH

Description:

Fmoc-His(3-Me)-OH, also known as 9-fluorenylmethoxycarbonyl-L-histidine(3-methyl), is a protected form of the amino acid histidine, which is commonly used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions at the carboxyl end of the amino acid during peptide assembly. The presence of the 3-methyl substitution on the histidine side chain alters its properties, potentially influencing the peptide's overall structure and function. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but less soluble in water. Its stability under standard laboratory conditions makes it suitable for various applications in organic synthesis and biochemistry. The CAS number 252049-16-4 uniquely identifies this compound, facilitating its recognition in chemical databases and literature. Overall, Fmoc-His(3-Me)-OH is a valuable building block in the synthesis of peptides with specific functional characteristics.

Formula: C₂₂H₂₁N₃O₄

Synonyms:

• Fmoc-His(Pi-Me)-Oh
• Fmoc-Histidine(3-Me)-Oh
• Fmoc-N-P-Methyl-L-Histidine
• N-(9-Fluorenylmethoxycarbonyl)-N-Imidazole-3-Methyl-L-Histidine
• N-Alpha-Fmoc-N-Pi-Methyl-L-Histidine
• Fmoc-His(p-Me)-OH
• L-Histidine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-methyl-

Fmoc-His(3-Me)-OH

CAS: 252049-16-4

Bachem ID: 4028985.

Formula: C₂₂H₂₁N₃O₄

Purity: 99.1%

Color and Shape: White Powder

Molecular weight: 391.43

Ref: 01-4028985

(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(3-methylimidazol-4-yl)propanoic acid

CAS: 252049-16-4

Formula: C₂₂H₂₁N₃O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 391.4198

Ref: IN-DA00BEW7

Fmoc-His(3-Me)-OH Fmoc-His(p-Me)-OH

CAS: 252049-16-4

Fmoc-His(3-Me)-OH Fmoc-His(p-Me)-OH

Formula: C₂₂H₂₁N₃O₄

Purity: ≥95%

Color and Shape: white powder

Molecular weight: 391.42g/mol

Ref: 54-OR36415

Fmoc-3-methyl-Histidine

CAS: 252049-16-4

Formula: C₂₂H₂₁N₃O₄

Molecular weight: 391.43

Ref: 4Z-H-018022

Fmoc-His(3-Me)-OH

CAS: 252049-16-4

Fmoc-His(3-Me)-OH is a synthetic amino acid that is used in the synthesis of peptides. It is potent inhibitor of L-type calcium channels, which are involved in the regulation of muscle contraction and vasoconstriction. Fmoc-His(3-Me)-OH has been shown to be effective at inhibiting L-type calcium channels in rat skeletal muscle.

Formula: C₂₂H₂₁N₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 391.42 g/mol

Ref: 3D-FF49488

FMOC-HIS(3-ME)-OH

CAS: 252049-16-4

Formula: C₂₂H₂₁N₃O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 391.427

Ref: 10-F475401