Description:2-Bromo-1,4-dimethoxybenzene, with the CAS number 25245-34-5, is an organic compound belonging to the class of brominated aromatic compounds. It features a benzene ring substituted with two methoxy groups (-OCH3) at the 1 and 4 positions and a bromine atom at the 2 position. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is characterized by its moderate solubility in organic solvents such as ethanol and ether, while being less soluble in water due to the hydrophobic nature of the aromatic ring. The presence of bromine and methoxy groups influences its reactivity, making it a useful intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Additionally, the compound may exhibit interesting electronic properties due to the electron-donating effects of the methoxy groups and the electron-withdrawing nature of the bromine atom, which can affect its behavior in various chemical reactions. Safety precautions should be taken when handling this compound, as it may pose health risks.
2-Bromo-1,4-dimethoxybenzene has been used in preparation of S-(-)-2-[N-(trifluoroacetyl)amino]-1-(2,5-dimethoxy-4- bromophenyl)-1-propanone, 1,4-bis{4-[2-(4-pyridyl)ethenyl]phenyl}butadiyne and 1,4-bis{2,5-dimethoxy-4-[2-(4-pyridyl)ethenyl]phenyl}butadiyne and 1-bromo-4-iodo-2,5-dimethoxybenzene. It …
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