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CAS 25255-33-8

:

(arg8,gly-oh9)-vasopressin

Description:
The chemical substance known as (Arg8,Gly-OH9)-vasopressin, with the CAS number 25255-33-8, is a synthetic analog of the naturally occurring hormone vasopressin, which is also known as antidiuretic hormone (ADH). This compound is characterized by its structure, which includes an arginine residue at position 8 and a glycine residue with a hydroxyl group at position 9, differentiating it from the native hormone. It exhibits properties typical of peptide hormones, such as solubility in water and the ability to interact with specific receptors in the body, primarily the vasopressin receptors. This analog is often studied for its potential therapeutic applications, particularly in conditions related to water balance and blood pressure regulation. Its pharmacological effects may include vasoconstriction and modulation of renal water reabsorption. As a synthetic derivative, it may also have altered stability and bioavailability compared to the natural hormone, making it a subject of interest in both clinical and research settings.
Formula:C46H64N14O13S2
InChI:InChI=1/C46H64N14O13S2/c47-27-22-74-75-23-33(45(73)60-17-5-9-34(60)44(72)55-28(8-4-16-52-46(50)51)39(67)53-21-37(64)65)59-43(71)32(20-36(49)63)58-40(68)29(14-15-35(48)62)54-41(69)31(18-24-6-2-1-3-7-24)57-42(70)30(56-38(27)66)19-25-10-12-26(61)13-11-25/h1-3,6-7,10-13,27-34,61H,4-5,8-9,14-23,47H2,(H2,48,62)(H2,49,63)(H,53,67)(H,54,69)(H,55,72)(H,56,66)(H,57,70)(H,58,68)(H,59,71)(H,64,65)(H4,50,51,52)/t27-,28-,29-,30-,31+,32-,33-,34?/m0/s1
Synonyms:
  • Argipressin, gly(OH9)-
  • (Arg(8)-gly-OH9)vasopressin
  • 8-L-Arginine-9-glycine-vasopressin
  • Vasopressin, 8-L-arginine-9-glycine-
  • 1-{[(4R,7S,10S,13R,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-N~5~-(diaminomethylidene)-L-ornithylglycine
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