CAS 252642-12-9

L-Phenylalanine,L-leucyl-L-valyl-L-glutaminyl-L-prolyl-L-arginylglycyl-L-seryl-L-arginyl-L-asparaginylglycyl-L-prolylglycyl-L-prolyl-L-tryptophyl-L-glutaminylglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginy

Description:

The substance you are referring to, with the name "L-Phenylalanine, L-leucyl-L-valyl-L-glutaminyl-L-prolyl-L-arginylglycyl-L-seryl-L-arginyl-L-asparaginylglycyl-L-prolylglycyl-L-prolyl-L-tryptophyl-L-glutaminylglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginy" and CAS number "252642-12-9," is a complex peptide composed of multiple amino acids. This compound is characterized by its sequence of amino acids, which includes essential and non-essential amino acids, contributing to its potential biological activity. Peptides like this one can play significant roles in various physiological processes, including hormone regulation, immune response, and neurotransmission. The presence of multiple arginine and glycine residues suggests potential for interaction with biological receptors or enzymes. Additionally, the peptide's solubility, stability, and reactivity can be influenced by its amino acid composition and sequence, which may affect its applications in research or therapeutic contexts. Overall, this substance represents a complex structure that may have unique biochemical properties.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Synonyms:

• Apelin(human)

Apelin-36 (human)

CAS: 252642-12-9

The orphan G protein-coupled receptor APJ has been shown to be a coreceptor for human and simian immunodeficiency virus (HIV and SIV) strains. As long as apelin is an endogenous ligand for the APJ receptor, inhibitory effects of apelin peptides on HIV infection have been examined and it has been found that the apelin peptides inhibit the entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ. For apelin-36 the strongest inhibitory efficiency has been reported.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: > 96%

Color and Shape: White Powder

Molecular weight: 4195.89

Ref: 01-4034005

Apelin 36

CAS: 252642-12-9

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: 98%

Molecular weight: 4195.8285

Ref: IN-DA0039XR

Apelin-36(human)

CAS: 252642-12-9

Endogenous APJ agonist, EC50=20nM, regulates cardiovascular function, fluid balance, and feeding; blocks certain HIV strains.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 4195.87

Ref: TM-TP2093

Apelin-36 Human

CAS: 252642-12-9

Apelin-36 (human) is derived from the apelin peptide which acts as a ligand for the apelin receptor (APJ) G protein coupled receptor and is a substrate for angiotensin converting enzyme 2. Preprapelin, encoded for by APLN located on Xq25-26.1, is cleaved to form either apelin 36, apelin 17, apelin 13, or apelin 12. As a member of the adipokine hormone family, which are involved in processes such as vascular homeostasis and angiogenesis, apelin is secreted from adipose tissue.Both apelin and the apelin receptor are widely distributed around the body thus apelin has been found to be associated with cardiovascular diseases, obesity, diabetes and cancer. Studies exploring myocardial infarction showed there to be greater apelin mRNA expression during human heart failure compared to in healthy tissue. Apelin protects against heart failure due to, the pyroglutamyl form of apelin, playing a role in decreasing infarct size of myocardial infarctions. Furthermore in rats with hypertension, the expression of apelin and APJ was decreased.

Molecular weight: 4,193.3 g/mol

Ref: 3D-CRB1000048

Apelin-36

CAS: 252642-12-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Molecular weight: 4,195.9 g/mol

Ref: 3D-PP50521

H-LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF-OH

CAS: 252642-12-9

Peptide H-LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Molecular weight: 4,195.89 g/mol

Ref: 3D-PP49914

Apelin-36, human

CAS: 252642-12-9

Custom research peptide; min purity 95%.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: Min. 95%

Molecular weight: 4,195.92 g/mol

Ref: 3D-PA16915

Apelin-36 (Human)

CAS: 252642-12-9

Apelin-36 is a peptide hormone that is derived from a larger precursor protein. It is a member of the apelin peptide family, which is involved in regulating cardiovascular and metabolic functions.
Apelin-36 binds to a G protein-coupled receptor called APJ (apelin receptor), which is widely expressed in various tissues. The interaction between apelin-36 and APJ receptor leads to a range of physiological effects, such as cardiac contractility stimulation and blood pressure suppression as well as lowering body weight and improving glucose homeostasis.
Research has shown that apelin-36 may have therapeutic potential in the treatment of cardiovascular diseases, such as hypertension and heart failure, as well as metabolic disorders, such as obesity and diabetes. Apelin-36 has also been implicated in other physiological processes, including inflammation, angiogenesis, and cancer progression. This product is available as a 0.1 mg vial.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: Min. 95%

Molecular weight: 4,195.8 g/mol

Ref: 3D-PAP-4362-S

Apelin-36 (human)

CAS: 252642-12-9

Apelin-36 is a human apelin protein. It is involved in the regulation of appetite and energy expenditure. Apelin-36 has been shown to be an independent predictor of body mass index and insulin resistance in women with polycystic ovary syndrome. Apelin-36 is also an indicator of the risk for cardiovascular disease, stroke, and type 2 diabetes mellitus. This molecule can be measured using a Western blot assay method on ovary homogenates. The level of apelin-36 can be used as a diagnostic tool for determining insulin resistance and overweight status.

Formula: C₁₈₄H₂₉₇N₆₉O₄₃S

Purity: Min. 95%

Molecular weight: 4,195.83 g/mol

Ref: 3D-FA109395