CAS 252920-94-8: Solabegron

Description: Solabegron is a selective beta-3 adrenergic receptor agonist, primarily investigated for its potential therapeutic applications in treating overactive bladder and other conditions related to urinary incontinence. As a chemical entity, it exhibits a unique structure that allows it to selectively activate beta-3 adrenergic receptors, which play a crucial role in bladder relaxation and increased capacity. Solabegron is characterized by its moderate lipophilicity, which influences its absorption and distribution in biological systems. The compound is typically administered orally and has been studied for its pharmacokinetic properties, including metabolism and excretion pathways. Its safety profile and efficacy have been evaluated in clinical trials, highlighting its potential benefits over traditional treatments for urinary disorders. However, as with any pharmacological agent, the therapeutic use of Solabegron may be accompanied by side effects, which necessitate careful consideration in clinical settings. Overall, Solabegron represents a promising advancement in the management of bladder-related conditions, reflecting ongoing research in the field of urology and pharmacotherapy.

Formula: C₂₃H₂₃ClN₂O₃

InChI: InChI=1S/C23H23ClN2O3/c24-20-8-2-6-18(13-20)22(27)15-25-10-11-26-21-9-3-5-17(14-21)16-4-1-7-19(12-16)23(28)29/h1-9,12-14,22,25-27H,10-11,15H2,(H,28,29)/t22-/m0/s1

InChI key: InChIKey=LLDXOPKUNJTIRF-QFIPXVFZSA-N

SMILES: O=C(O)C1=CC=CC(=C1)C2=CC=CC(=C2)NCCNCC(O)C=3C=CC=C(Cl)C3

Synonyms:

• (-)-(R)-3′-[[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]biphenyl-3-carboxylic acid
• 3′-[[2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino][1,1′-biphenyl]-3-carboxylic acid
• Gw 427353
• Solabegron
• [1,1′-Biphenyl]-3-carboxylic acid, 3′-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]amino]-

Solabegron

CAS: 252920-94-8

Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese …

• Formula: C₂₃H₂₃ClN₂O₃
• Purity: 97.89%
• Color and Shape: Solid
• Molecular weight: 410.89

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-

CAS: 252920-94-8

• Formula: C₂₃H₂₃ClN₂O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 410.8933

Solabegron-d8 HCl

CAS: 252920-94-8

• Formula: C₂₃H₁₅ClN₂O₃D₈·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 418.95 36.46

Solabegron

CAS: 252920-94-8

• Formula: C₂₃H₂₃ClN₂O₃
• Color and Shape: Neat
• Molecular weight: 410.893

Solabegron-13C6

CAS: 252920-94-8

• Formula: C₆C₁₇H₂₃ClN₂O₃
• Color and Shape: Neat
• Molecular weight: 416.849

Solabegron

CAS: 252920-94-8

Solabegron is a drug that has clinical relevance for the treatment of bladder disorders. It …

• Formula: C₂₃H₂₃ClN₂O₃
• Purity: Min. 95%
• Molecular weight: 410.89 g/mol