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CAS 2531685-87-5

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  • p53 Stabilizer 2

    CAS:
    <p>p53 Stabilizer 2 (Compound 17a16) is a p53 stabilizing agent. It can induce S-phase arrest and apoptosis in both p53-functional and p53-deficient cancer cells. Additionally, p53 Stabilizer 2 triggers mitochondrial stress and activates two immune checkpoint pathways: NA-PKcs dependent p53 stabilization and the ATR-Chk1 axis activation. It also inhibits tumor growth in p53-deficient xenograft models.</p>
    Formula:C30H37NO7Se
    Color and Shape:Solid
    Molecular weight:602.58