CAS 253337-60-9

(aR)-a-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine Hydrochloride

CAS: 253337-60-9

Formula: C₂₂H₂₅N

Purity: 98%

Color and Shape: Solid

Molecular weight: 303.4406

Ref: IN-DA00BF05

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(m-tolyl)propan-1-amine

CAS: 253337-60-9

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(m-tolyl)propan-1-amine

Purity: 98%

Molecular weight: 303.44g/mol

Ref: 54-OR89592

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(m-tolyl)propan-1-amine

CAS: 253337-60-9

Purity: 98%

Molecular weight: 303.4490051269531

Ref: 10-F789611

(AlphaR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine Hydrochloride

Controlled Product

CAS: 253337-60-9

Applications (αR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).
References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003), Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),

Formula: C₂₂H₂₅N

Color and Shape: Neat

Molecular weight: 303.44

Ref: TR-M322070

Cinacalcet impurity E hydrochloride

CAS: 253337-60-9

Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.

Formula: C₂₂H₂₅N·HCl

Purity: Min. 95%

Molecular weight: 339.9 g/mol

Ref: 3D-IC106470