CAS 253863-00-2

Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-, hydrochloride (1:1)

Description:

Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-, hydrochloride (1:1) is a chemical compound characterized by its complex structure, which includes a benzonitrile moiety and a piperazine derivative. This substance typically appears as a white to off-white solid and is soluble in polar solvents such as water and methanol, owing to the presence of the hydrochloride salt form. The compound exhibits biological activity, often studied for its potential pharmacological properties, particularly in the context of medicinal chemistry. Its molecular structure suggests potential interactions with biological targets, making it of interest in drug development. The presence of chlorine and the imidazole ring may contribute to its reactivity and biological activity. As with many chemical substances, handling should be done with care, following appropriate safety protocols due to potential toxicity and reactivity.

Formula: C₂₂H₂₀ClN₅O·ClH

InChI: InChI=1S/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H

InChI key: InChIKey=YNBSQYGTJLIPJS-UHFFFAOYSA-N

SMILES: O=C1N(CCN(CC=2N(CC3=CC=C(C#N)C=C3)C=NC2)C1)C4=CC(Cl)=CC=C4.Cl

Synonyms:

• Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-, hydrochloride (1:1)
• L 778123
• Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-, monohydrochloride

L-778,123 (hydrochloride)

CAS: 253863-00-2

Formula: C₂₂H₂₁Cl₂N₅O

Purity: 98%

Molecular weight: 442.3410

Ref: IN-DA003R6Z

L-778123 hydrochloride

CAS: 253863-00-2

L-778123 hydrochloride

Purity: ≥90%

Molecular weight: 442.34g/mol

Ref: 54-BUP05862

L-778123 hydrochloride

CAS: 253863-00-2

The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.

Formula: C₂₂H₂₁Cl₂N₅O

Purity: 93.93% - 98.51%

Color and Shape: Solid

Molecular weight: 442.34

Ref: TM-T3182

L 778123

CAS: 253863-00-2

Inhibitor of farnesyltransferase and geranylgeranyltransferase 1

Formula: C₂₂H₂₀ClN₅O·ClH

Purity: Min. 95%

Molecular weight: 442.34 g/mol

Ref: 3D-FL137694