CAS 25399-48-8
:2,3,4-Tris-O-(triMethylsilyl) 7-Epi ClindaMycin
Description:
2,3,4-Tris-O-(trimethylsilyl) 7-epi clindamycin is a chemically modified derivative of clindamycin, an antibiotic used primarily for treating bacterial infections. This compound features three trimethylsilyl groups, which enhance its stability and solubility in organic solvents, making it useful in various synthetic applications. The presence of these silyl groups can also facilitate the protection of hydroxyl functionalities during chemical reactions. The compound retains the core structure of clindamycin, which is a lincosamide antibiotic, thus maintaining its potential biological activity against certain Gram-positive bacteria. Its molecular structure includes a cyclic amine and a thioether linkage, characteristic of lincosamides. The modification with trimethylsilyl groups may influence its pharmacokinetics and bioavailability. As with many chemical substances, handling should be done with care, considering potential hazards and the need for proper safety protocols. Overall, 2,3,4-Tris-O-(trimethylsilyl) 7-epi clindamycin represents a specialized compound with applications in medicinal chemistry and research.
Formula:C27H57ClN2O5SSi3
Synonyms:- D-erythro-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-2,3,4-tris-O-(trimethylsilyl)-, trans- α- (8CI)
- 2,3,4-Tris-O-(triMethylsilyl) 7-Epi ClindaMycin
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