CAS 2541-37-9: Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-

Description: Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-, commonly known as a synthetic corticosteroid, exhibits several notable characteristics. This compound is a derivative of progesterone and is characterized by its structural modifications, including the presence of fluorine atoms and an acetoxy group, which enhance its biological activity and stability. It typically exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in treating conditions like asthma, allergies, and autoimmune disorders. The specific stereochemistry indicated by the (6α,11β,16α) configuration plays a crucial role in its pharmacological effects, influencing receptor binding and activity. Additionally, the compound's solubility and stability can vary based on its formulation and the presence of other excipients. As with many corticosteroids, careful consideration of dosage and potential side effects is essential in clinical use, including the risk of adrenal suppression and other systemic effects.

Formula: C₂₄H₃₀F₂O₅

InChI: InChI=1S/C24H30F2O5/c1-12-7-15-16-9-18(25)17-8-14(28)5-6-23(17,4)24(16,26)20(30)10-22(15,3)21(12)19(29)11-31-13(2)27/h5-6,8,12,15-16,18,20-21,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,20+,21-,22+,23+,24+/m1/s1

InChI key: InChIKey=FHRAHFYXLDXYML-CDACMRRYSA-N

SMILES: O=C1C=CC2(C(=C1)C(F)CC3C4CC(C)C(C(=O)COC(=O)C)C4(C)CC(O)C32F)C

Synonyms:

• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,21-dihydroxy-16α-methyl-, 21-acetate

Flumethasone Impurity 10

CAS: 2541-37-9

• Formula: C₂₄H₃₀F₂O₅
• Molecular weight: 436.50

Difluocortolone 21-Acetate

CAS: 2541-37-9

• Formula: C₂₄H₃₀F₂O₅
• Color and Shape: Neat
• Molecular weight: 436.489

Diflucortolone-d3 21-Acetate

CAS: 2541-37-9

Applications Diflucortolone-d3 (D445617) derivative. A glucocorticoid.

• Formula: C₂₄H₂₇D₃F₂O₅
• Color and Shape: Neat
• Molecular weight: 439.51

Flumethasone Impurity 10

CAS: 2541-37-9

Flumethasone Impurity 10 is a synthetic drug product. It is for research and development purposes …

• Purity: Min. 95%