CAS 2541626-73-5

Benzoic acid, 4-[[7-cyclopentyl-6-[(dimethylamino)carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-

Description:

Benzoic acid, 4-[[7-cyclopentyl-6-[(dimethylamino)carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]- is a complex organic compound characterized by its structural features, which include a benzoic acid moiety and a pyrrolopyrimidine derivative. This compound typically exhibits properties such as being a solid at room temperature, with potential solubility in organic solvents due to its hydrophobic cyclopentyl group and polar dimethylamino carbonyl functionality. The presence of the benzoic acid group suggests acidic properties, allowing it to participate in acid-base reactions. Additionally, the compound may exhibit biological activity, potentially serving as a pharmacophore in medicinal chemistry, given the presence of the pyrrolopyrimidine structure, which is often associated with various biological targets. Its molecular interactions could be influenced by hydrogen bonding and π-π stacking due to the aromatic nature of the benzoic acid. Overall, this compound's unique structure may lead to interesting chemical behavior and potential applications in pharmaceuticals or agrochemicals.

Formula: C₂₁H₂₃N₅O₃

Synonyms:

• Benzoic acid, 4-[[7-cyclopentyl-6-[(dimethylamino)carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-

Aurora-A ligand 1

CAS: 2541626-73-5

Aurora-A ligand 1 is a potent and selective inhibitor of Aurora-A, exhibiting a dissociation constant (Kd) of 0.85 nM. It serves as a target protein ligand [PROTAC target protein ligand] in the development of PROTAC Aurora-A degraders with antitumor activity. Additionally, Aurora-A ligand 1 is utilized in the synthesis of HLB-0532259, which exhibits antitumor effects against neuroblastoma.

Formula: C₂₁H₂₃N₅O₃

Color and Shape: Solid

Molecular weight: 393.439

Ref: TM-T204142