CAS 254912-65-7

rel-1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]ethanone

Description:

The chemical substance known as rel-1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]ethanone, with the CAS number 254912-65-7, is a complex organic compound characterized by its multi-functional structure. It features a piperazine moiety, which is often associated with biological activity, and a dioxolane ring that contributes to its stability and solubility. The presence of a dichlorophenyl group suggests potential interactions with biological targets, making it of interest in medicinal chemistry. The imidazole ring may also enhance its pharmacological properties, potentially influencing its mechanism of action. This compound is likely to exhibit specific physicochemical properties, such as solubility in organic solvents and moderate stability under standard conditions. Its intricate structure indicates potential for diverse applications, particularly in drug development, where it may serve as a lead compound for further optimization. However, detailed studies would be necessary to fully elucidate its biological activity and therapeutic potential.

Formula: C₂₆H₂₈Cl₂N₄O₅

InChI: InChI=1/C26H28Cl2N4O5/c1-19(33)31-10-12-32(34,13-11-31)21-3-5-22(6-4-21)35-15-23-16-36-26(37-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/s2

InChI key: InChIKey=TVMVVRYAPWZNJP-MKNUCDGGNA-N

SMILES: C([C@]1(O[C@@H](COC2=CC=C(C=C2)N3(=O)CCN(C(C)=O)CC3)CO1)C4=C(Cl)C=C(Cl)C=C4)N5C=CN=C5

Synonyms:

• Piperazine, 1-acetyl-4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, 4-oxide, rel-
• Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]-, rel-
• R 053165
• rel-1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]ethanone
• KetoconazoleN-Oxide

Ketoconazole N-Oxide (Ketoconazole Metabolite (M13))

CAS: 254912-65-7

Formula: C₂₆H₂₈Cl₂N₄O₅

Color and Shape: White To Off-White Solid

Molecular weight: 547.43

Ref: 4Z-K-0111

Ketoconazole N-Oxide

Controlled Product

CAS: 254912-65-7

Formula: C₂₆H₂₈Cl₂N₄O₅

Color and Shape: Neat

Molecular weight: 547.43

Ref: 86-MM0145.07

Ketoconazol N-Oxide

CAS: 254912-65-7

Formula: C₂₆H₂₈Cl₂N₄O₅

Molecular weight: 547.43

Ref: ST-EA-CP-K2014

Ketoconazole N-​Oxide

Controlled Product

CAS: 254912-65-7

Applications Ketoconazole N-​Oxide is an impure analogue of Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.
References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)

Formula: C₂₆H₂₈Cl₂N₄O₅

Color and Shape: Off-White

Molecular weight: 547.43

Ref: TR-K186005

Ketoconazole N-oxide

CAS: 254912-65-7

Please enquire for more information about Ketoconazole N-oxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₆H₂₈Cl₂N₄O₅

Purity: Min. 95%

Molecular weight: 547.4 g/mol

Ref: 3D-EKA91265