EGFR ligand-11, identified by its CAS number 2550394-08-4, is a synthetic peptide that acts as a ligand for the epidermal growth factor receptor (EGFR). This receptor is crucial in various cellular processes, including proliferation, differentiation, and survival, making it a significant target in cancer research and therapy. The characteristics of EGFR ligand-11 include its ability to bind specifically to the EGFR, thereby activating downstream signaling pathways that can influence cell behavior. Typically, such ligands are designed to mimic natural substrates or enhance receptor activation, potentially leading to increased cellular responses. The peptide's structure often includes specific amino acid sequences that facilitate high-affinity interactions with the receptor. Additionally, EGFR ligand-11 may exhibit properties such as solubility in aqueous solutions, stability under physiological conditions, and the potential for modification to enhance its therapeutic efficacy. Its applications are primarily in biomedical research, particularly in studies focused on cancer biology and the development of targeted therapies.

EGFR ligand-11

2550394-08-4: EGFR ligand-11, identified by its CAS number 2550394-08-4, is a synthetic peptide that acts as a ligand for the epidermal growth factor receptor (EGFR). This receptor is crucial in various cellular processes, including proliferation, differentiation, and survival, making it a significant target in cancer research and therapy. The characteristics of EGFR ligand-11 include its ability to bind specifically to the EGFR, thereby activating downstream signaling pathways that can influence cell behavior. Typically, such ligands are designed to mimic natural substrates or enhance receptor activation, potentially leading to increased cellular responses. The peptide's structure often includes specific amino acid sequences that facilitate high-affinity interactions with the receptor. Additionally, EGFR ligand-11 may exhibit properties such as solubility in aqueous solutions, stability under physiological conditions, and the potential for modification to enhance its therapeutic efficacy. Its applications are primarily in biomedical research, particularly in studies focused on cancer biology and the development of targeted therapies.

<p>EGF Rligand-11, a target protein ligand for EGFR, is utilized in the synthesis of PROTAC MS154.</p>

CAS 2550394-08-4

EGFR ligand-11

EGFR ligand-11

Ref: TM-T201728